88125-0
Escherichia coli enterotoxigenic gene panel - Specimen by NAA with probe detection
Active
87321-6 Escherichia coli enterotoxigenic sta gene [Presence] in Isolate by NAA with probe detection
Part Descriptions
LP262495-7 Escherichia coli enterotoxigenic sta gene
Enterotoxigenic Escherichia coli (ETEC) produces a heat-labile (LT) and a heat-stable (ST) enterotoxin, both of which cause severe diarrhea in both humans and animals. ST is an extracellular toxin which is comprised of a methanol-soluble (STa) toxin and a methanol-insoluble (STb) toxin. The sta gene encodes the STa toxin and the stb gene encodes the STb toxin. [UniProt: Q70Q79]; [UniProt: Q70Q73] STa combines to its enterocyte receptor, guanylate cyclase, which causes intestinal secretion and diarrhea. PMID: 8528070 The STb enterocyte receptor is the protein sulfatide. After STb binds to sulfatide, it is engulfed by the enterocyte. It then activates the pertussis toxin-sensitive G protein which opens the ligand-gated calcium ion channel, allowing an influx of calcium ions. A subsequent secretion of chloride ions, stimulation of arachidonic acid release, and production of prostaglandin E2 and 5-dyroxytryptamine leads to an efflux of water, bicarbonate ions, sodium ions, and chloride ions into the intestinal space, all of which leads to watery diarrhea. PMID: 23716609
Source: Regenstrief LOINC
Observation Required in Panel
Optional
Fully-Specified Name
- Component
- Escherichia coli enterotoxigenic sta gene
- Property
- PrThr
- Time
- Pt
- System
- Isolate
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- ETEC sta gene Islt Ql NAA+probe
- Display Name
- E. coli enterotoxigenic sta gene NAA+probe Ql (Isol)
- Consumer Name Alpha Get Info
- Escherichia coli enterotoxigenic sta gene
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.63
- Last Updated
- Version 2.63
- Order vs. Observation
- Both
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 88125-0 | Escherichia coli enterotoxigenic gene panel - Specimen by NAA with probe detection |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Escherichia coli enterotoxigenic sta-Gen: |
| es-ES | Spanish (Spain) | Gen sta Escherichia coli enterotoxigenico: |
| es-MX | Spanish (Mexico) | Gen sta enterotoxigénico de Escherichia coli: |
| fr-FR | French (France) | Escherichia coli entérotoxinogène sta gène: |
| it-IT | Italian (Italy) | Escherichia coli enterotossigeni gene sta: Synonyms: ETEC Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA |
| nl-NL | Dutch (Netherlands) | Escherichia coli enterotoxine-gen hittegevoelig toxine: Synonyms: E.coli; |
| zh-CN | Chinese (China) | 大肠埃希菌肠产毒素型 sta 基因: Synonyms: E coli; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
87322-4 Escherichia coli enterotoxigenic stb gene [Presence] in Isolate by NAA with probe detection
Part Descriptions
LP262492-4 Escherichia coli enterotoxigenic stb gene
Enterotoxigenic Escherichia coli (ETEC) produces a heat-labile (LT) and a heat-stable (ST) enterotoxin, both of which cause severe diarrhea in both humans and animals. ST is an extracellular toxin which is comprised of a methanol-soluble (STa) toxin and a methanol-insoluble (STb) toxin. The sta gene encodes the STa toxin and the stb gene encodes the STb toxin. [UniProt: Q70Q79]; [UniProt: Q70Q73] STa combines to its enterocyte receptor, guanylate cyclase, which causes intestinal secretion and diarrhea. PMID: 8528070 The STb enterocyte receptor is the protein sulfatide. After STb binds to sulfatide, it is engulfed by the enterocyte. It then activates the pertussis toxin-sensitive G protein which opens the ligand-gated calcium ion channel, allowing an influx of calcium ions. A subsequent secretion of chloride ions, stimulation of arachidonic acid release, and production of prostaglandin E2 and 5-dyroxytryptamine leads to an efflux of water, bicarbonate ions, sodium ions, and chloride ions into the intestinal space, all of which leads to watery diarrhea. PMID: 23716609
Source: Regenstrief LOINC
Observation Required in Panel
Optional
Fully-Specified Name
- Component
- Escherichia coli enterotoxigenic stb gene
- Property
- PrThr
- Time
- Pt
- System
- Isolate
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- ETEC stb gene Islt Ql NAA+probe
- Display Name
- E. coli enterotoxigenic stb gene NAA+probe Ql (Isol)
- Consumer Name Alpha Get Info
- Escherichia coli enterotoxigenic stb gene
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.63
- Last Updated
- Version 2.63
- Order vs. Observation
- Both
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 88125-0 | Escherichia coli enterotoxigenic gene panel - Specimen by NAA with probe detection |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Escherichia coli enterotoxigenic stb-Gen: |
| es-ES | Spanish (Spain) | Gen stb Escherichia coli enterotoxigenico: |
| es-MX | Spanish (Mexico) | Gen stb enterotoxigénico de Escherichia coli: |
| fr-FR | French (France) | Escherichia coli entérotoxinogène stb gène: |
| it-IT | Italian (Italy) | Escherichia coli enterotossigeni gene stb: Synonyms: ETEC Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA |
| nl-NL | Dutch (Netherlands) | Escherichia coli enterotoxine-gen sta-gen: Synonyms: E.coli; |
| zh-CN | Chinese (China) | 大肠埃希菌肠产毒素型 stb 基因: Synonyms: E coli; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.