88575-6
Onchocerca sp IgG4 Ab [Presence] in Serum by Immunoassay
Active
Part Descriptions
LP14830-1 Onchocerca sp
Onchocerca is a genus of nematode (roundworm) that includes O. volvulus, the causative agent of the human disease known as River Blindness. River blindness results in vision impairment and can also cause skin disease and debilitating itching. Onchocerciasis is the second-leading infectious cause of blindness in humans. [https://www.cdc.gov/parasites/onchocerciasis/index.html] Other species of Onchocerca include O. lupi, which can cause disease in dogs, cats, and humans, O. gutturosa and O. lienalis, which affect cattle, and O. cervicalis, which affects horses.
Source: Regenstrief LOINC
LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Onchocerca sp Ab.IgG4
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IA
Additional Names
- Long Common Name
- Onchocerca sp IgG4 Ab [Presence] in Serum by Immunoassay
- Short Name
- Onchocerca IgG4 Ser Ql IA
- Display Name
- Onchocerca sp IgG4 IA Ql (S)
- Consumer Name Alpha Get Info
- Onchocerca sp IgG4 antibody, Blood
Example Answer List: LL744-4
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.64
- Last Updated
- Version 2.64 (ADD)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Παράσιτο Onchocerca sp Ab.IgG4: Synonyms: PrThr Παράσιτο Onchocerca sp |
| es-ES | Spanish (Spain) | Onchocerca sp IgG4: |
| es-MX | Spanish (Mexico) | Onchocerca sp Ab.IgG4: |
| et-EE | Estonian (Estonia) | Onchocerca sp antikehad.IgG4: Synonyms: Järgarvuline Juhuslik Seerum |
| fr-CA | French (Canada) | Onchocerca sp, IgG4: |
| fr-BE | French (Belgium) | Onchocerca sp Anticorps. IgG4: Synonyms: Anticorps |
| fr-FR | French (France) | Onchocerca Ac IgG4: |
| it-IT | Italian (Italy) | Onchocerca sp Ab.IgG4: Synonyms: Anticorpi IgG4 anticorpo Immunoassay Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero |
| nl-NL | Dutch (Netherlands) | Onchocerca sp. As.IgG4: Synonyms: antistof; |
| ru-RU | Russian (Russian Federation) | Onchocerca sp Ат.IgG4: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Onchocerca sp Ab.IgG4: Synonyms: İmmünölçüm, immünoassay Mevcut |
| zh-CN | Chinese (China) | 盘尾属单个未知种 抗体.IgG4: Synonyms: Ab.IgG4; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=88575-6
LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://