88625-9

Cytomegalovirus [Presence] in Ocular fluid by Organism specific culture

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Part Descriptions

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

LP6429-7   Organism specific culture
An organism-specific culture contains nutrients that optimize the growth of a specific organism and inhibitors that prevent the growth of competing organisms. Source: Regenstrief LOINC

LP7448-6   Ocular fld
The "Ocular fld" System in LOINC encompasses aqueous humor and vitreous humor. Aqueous humor is found in the anterior and posterior chambers of the eye, both of which are located anterior to the lens. Vitreous humor is found in the vitreous chamber, which is located between the lens and the retina. This System is used for LOINC terms that represent tests run on either aqueous or vitreous fluid; it does not imply that both types of fluid are tested in any given instance. Source: Regenstrief LOINC

Fully-Specified Name

Component

Cytomegalovirus

Property

PrThr

Time

Pt

System

Ocular fld

Scale

Ord

Method

Organism specific culture

Additional Names

Short Name

CMV Ocflu Ql Cult

Display Name

CMV Org specific cx Ql (Ocular fluid)

Consumer Name Alpha Get Info

Cytomegalovirus (CMV) culture, Eye fluid

Example Answer List: LL744-4

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.64

Last Updated

Version 2.64

Order vs. Observation

Both

Member of these Groups Get Info

Language Variants Get Info

Related Names

• C&S
• CMV
• Cult
• Cultures
• Cytomegalo virus
• Cytomgal
• Eye fluid
• HHV-5
• Human Herpesvirus-5
• ID
• Infectious Disease
• InfectiousDisease
• Microbiology
• Occular Fluid
• OcFlu
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• Spec

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88625-9

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.