89373-5
Hepatitis A virus genotype in Specimen by NAA with probe detection
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Part Descriptions
LP16708-7 Hepatitis A virus
Hepatitis A virus (Hep A or HAV) is an RNA virus that causes an acute infectious disease of the liver and is usually spread by the fecal-oral route. It is transmitted by ingestion of contaminated food or water or through direct contact with an infectious person. In developing countries, and in regions with poor hygiene standards, the incidence of infection with this virus is high. HAV infection produces a self-limited disease that usually does not result in chronic infection or chronic liver disease. Overall occurrence acute liver failure from Hepatitis A is rare (approx. 0.5%). The risk for symptomatic infection is directly related to age, with >80% of adults having symptoms compatible with acute viral hepatitis and the majority of children having either asymptomatic or unrecognized infection. Antibody produced in response to HAV infection persists for life and confers protection against reinfection. The disease can be prevented by vaccination, and hepatitis A vaccine has been proven effective in controlling outbreaks worldwide.
Although HAV is excreted in the feces towards the end of the incubation period, specific diagnosis is made by the detection of HAV-specific IgM antibodies in the blood. IgM antibody is only present in the blood following an acute hepatitis A infection. It is detectable from one to two weeks after the initial infection and persists for up to 14 weeks. The presence of IgG antibody in the blood means that the acute stage of the illness is past and the person is immune to further infection. IgG antibody to HAV is also found in the blood following vaccination and tests for immunity to the virus are based on the detection of this antibody.
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Source: Wikipedia, Hepatitis A virus (Wikipedia)
LP16708-7 Hepatitis A virus
Hepatitis A virus (HAV) is a small, non-enveloped single-stranded RNA virus that belongs to the Picornaviridae family, genus Hepatovirus. HAV has six genotypes (I to VI) in which genotypes I to III are human isolates and IV to VI are only simian isolates. Genotypes I to III are subdivided into groups A and B. Genotype I is the most frequently reported. PMID: 15914081 The clinical manifestations of HAV infection can vary significantly and range from asymptomatic infection, usually seen in young children, to fulminant hepatitis, which can result in death. HAV has a global distribution, and transmission primarily occurs by the fecal-oral route. The risk of HAV transmission through blood products is very low, but there have been some reports of transmission through plasma products, mainly coagulation factors. PMID: 12186933 PMID: 1318940
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Hepatitis A virus genotype
- Property
- Type
- Time
- Pt
- System
- XXX
- Scale
- Nom
- Method
- Probe.amp.tar
Additional Names
- Short Name
- HAV Gentyp Spec NAA+probe
- Display Name
- HAV genotype NAA+probe (Specimen)
- Consumer Name Alpha Get Info
- Hepatitis A virus (HAV) genotype, Specimen
Example Answer List: LL4992-5
Source: Association of Public Health Laboratories| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Hepatitis A virus genotype I | LA28917-5 | ||
| Hepatitis A virus genotype II | LA28918-3 | ||
| Hepatitis A virus genotype III | LA28919-1 | ||
| Hepatitis A virus genotype IV | LA28920-9 | ||
| Hepatitis A virus genotype V | LA28921-7 | ||
| Hepatitis A virus subgenotype IA | LA28923-3 | ||
| Hepatitis A virus subgenotype IB | LA28924-1 | ||
| Hepatitis A virus subgenotype IIA | LA28925-8 | ||
| Hepatitis A virus subgenotype IIB | LA28926-6 | ||
| Hepatitis A virus subgenotype IIIA | LA28927-4 | ||
| Hepatitis A virus subgenotype IIIB | LA28928-2 | ||
| Not tested | LA13538-6 | ||
| Unable to complete sequencing | LA28929-0 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.64
- Last Updated
- Version 2.72
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG32762-3 | Hepatitis A virus |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Hepatitis-A-Virus Genotyp: Synonyms: Hepatovirus A; |
| el-GR | Greek (Greece) | Ιός Ηπατίτιδας Α γονότυπος: Synonyms: HAV |
| es-ES | Spanish (Spain) | Virus de la Hepatitis A Genotipo: |
| es-MX | Spanish (Mexico) | Genotipo del virus de la hepatitis A: |
| fr-BE | French (Belgium) | Virus de l'hépatite A Génotype: Synonyms: Génotype HVA |
| fr-CA | French (Canada) | Virus de l'hépatite A, Génotype: |
| fr-FR | French (France) | Hépatite A virus génotype: |
| it-IT | Italian (Italy) | Epatite A, virus, genotipo: Synonyms: Microbiologia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''epatite A |
| nl-NL | Dutch (Netherlands) | Hepatitis A-virus genotype: Synonyms: probe.amp.tar |
| ru-RU | Russian (Russian Federation) | Гепатита А вирус генотип: Synonyms: ДНК проба; |
| tr-TR | Turkish (Turkey) | Hepatit A virüsü genotip: Synonyms: Tür |
| zh-CN | Chinese (China) | 甲型肝炎病毒 基因型: Synonyms: A 型 HAV; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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