Version 2.78

Part Description

LP15747-6   Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

Fully-Specified Name

Component
Gentamicin
Property
Susc
Time
Pt
System
Isolate
Scale
Ord
Method
Genotyping

Additional Names

Short Name
Gentamicin Islt Genotyp
Display Name
Gentamicin Genotyping [Susc]
Consumer Name Alpha Get Info
Susceptibility to Gentamicin

Example Answer List: LL3666-6

Source: North Carolina State Laboratory of Public Health
Answer Code Score Answer ID
Resistant LA6676-6
Susceptible LA24225-7

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.69
Change Reason
Release 2.69: SYSTEM: Updated System to "Isolate" since this concept is about the susceptibility of the viral isolate to the drug, not the susceptibility of the specimen to the drug.;
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
89486-5 Mycobacterial susceptibility panel Qualitative by Genotype method
94053-6 Mycobacterium tuberculosis complex resistance panel by Molecular genetics method

Member of these Groups Get Info

LOINC Group Group Name
LG41057-7 GentamicinSusc|Isolate

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Gentamicin:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Ordinal:Genotypisierung
es-ES Spanish (Spain) Gentamicina:Susceptibilidad:Punto temporal:Aislado:Ord:Susceptibilidad al genotipo viral
es-MX Spanish (Mexico) Gentamicina:Susceptibilidad (microorganismos):Punto temporal:Aislado:Ordinal:Susceptibilidad del genotipo viral
et-EE Estonian (Estonia) Gentamütsiin:Susc:Pt:Is:Ord:Genotüpiseerimine
Synonyms: Isolaat Järgarvuline Juhuslik Tundlikkus
fr-FR French (France) Gentamicine:Sensibilité:Ponctuel:Isolat:Qualitatif:Génotypage
fr-BE French (Belgium) Gentamicine:Susceptibilité:Temps ponctuel:Isolat:Ordinal:Génotypage
fr-CA French (Canada) Gentamicine:Susceptibilité:Temps ponctuel:Isolat:Ordinal:Génotypage
it-IT Italian (Italy) Gentamicina:Susc:Pt:Isolato:Ord:Genotipizzazione
Synonyms: Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici Suscettibilità al genotipo virale
nl-NL Dutch (Netherlands) gentamicine:gevoeligheid:moment:isolaat:ordinaal:genotypering
ru-RU Russian (Russian Federation) Гентамицин:Чув:ТчкВрм:Изолят:Пор:Генотипирование
Synonyms: Вирусного генотипа чувствительность Порядковый Точка во времени;Момент Чувствительность (микроорганизмов)
tr-TR Turkish (Turkey) Gentamisin:Duyr:Zmlı:İzolat:Srl:Genotipleme
zh-CN Chinese (China) 庆大霉素:抗生素敏感性:时间点:分离株:序数型:基因分型
Synonyms: 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分离物;分离菌;分离菌株;隔离种群 基因型分型;基因型分析;基因型定型;基因定型;病毒基因型敏感性试验 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 正泰霉素;艮他霉素

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89481-6