89538-3
Neuronal nuclear type 2 Ab [Presence] in Cerebral spinal fluid by Line blot
Active
Term Description
This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.
Source: Regenstrief LOINC
Part Descriptions
LP14164-5 Neuronal nuclear type 2
Type I anti-neuronal nuclear antibody (ANNA-1) is present in patients with paraneoplastic syndromes (paraneoplastic sensory neuropathy or paraneoplastic encephalomyelitis) most commonly associated with small-cell lung carcinoma (SCLC). ANNA-2 is present in patients with midbrain encephalitis, cerebellar ataxia, eye movement disorders (usually opsoclonus), and occasionally myelopathy. Neoplasms most often associated with ANNA-2 are breast carcinoma and SCLC. ANNA-1 and ANNA-2 may be detectable before the associated neoplasm is detectable.
Source: ARUP Laboratories, ANNA
LP39195-0 Neuronal nuclear type 2 Ab
Neuronal nuclear antibody is a neuronal paraneoplastic antibody that has been associated with cerebellar degeneration in breast, small cell lung carcinoma and gynecological cancers.
Source: University of Birmingham, Neuronal antibodies
Fully-Specified Name
- Component
- Neuronal nuclear type 2 Ab
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- Line blot
Additional Names
- Short Name
- Hu2 Ab CSF Ql Line blot
- Display Name
- Neuronal nuclear type 2 Ab Line blot Ql (CSF)
- Consumer Name Alpha Get Info
- Neuronal nuclear type 2 antibody, Spinal fluid
Example Answer List: LL744-4
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Detected | LA11882-0 | ||
| Not detected | LA11883-8 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.64
- Last Updated
- Version 2.64
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG5089-0 | Neuronal nuclear type 2 Ab| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Anticuerpos Antineuronal nuclear tipo 2 Anticuerpos: |
| es-MX | Spanish (Mexico) | Nuclear neuronal tipo 2 Ab: |
| fr-FR | French (France) | Hu2 anticorps: |
| fr-CA | French (Canada) | Neuronal nucléaire de type 2, Ac: |
| it-IT | Italian (Italy) | Nucleare neuronale tipo 2 Ab: Synonyms: anticorpo Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | neuronaal nucleair type 2 As: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Typ 2 neuronalny jądrowy Ab: Synonyms: Przeciwciała do antygenów jądrowych komórek nerwowych typu 2 Przeciwciała onkoneuronalne |
| zh-CN | Chinese (China) | 神经元细胞核 2 型 抗体: Synonyms: Ⅱ Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=89538-3
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