Version 2.78

Term Description

Molecular testing for Hepatitis A in stool samples is useful in a variety of situations, including investigation of severe acute disease, Hepatitis A outbreaks, and diagnosis of infection in infants and young children.
Source: Regenstrief LOINC

Part Descriptions

LP16708-7   Hepatitis A virus
Hepatitis A virus (Hep A or HAV) is an RNA virus that causes an acute infectious disease of the liver and is usually spread by the fecal-oral route. It is transmitted by ingestion of contaminated food or water or through direct contact with an infectious person. In developing countries, and in regions with poor hygiene standards, the incidence of infection with this virus is high. HAV infection produces a self-limited disease that usually does not result in chronic infection or chronic liver disease. Overall occurrence acute liver failure from Hepatitis A is rare (approx. 0.5%). The risk for symptomatic infection is directly related to age, with >80% of adults having symptoms compatible with acute viral hepatitis and the majority of children having either asymptomatic or unrecognized infection. Antibody produced in response to HAV infection persists for life and confers protection against reinfection. The disease can be prevented by vaccination, and hepatitis A vaccine has been proven effective in controlling outbreaks worldwide.

Although HAV is excreted in the feces towards the end of the incubation period, specific diagnosis is made by the detection of HAV-specific IgM antibodies in the blood. IgM antibody is only present in the blood following an acute hepatitis A infection. It is detectable from one to two weeks after the initial infection and persists for up to 14 weeks. The presence of IgG antibody in the blood means that the acute stage of the illness is past and the person is immune to further infection. IgG antibody to HAV is also found in the blood following vaccination and tests for immunity to the virus are based on the detection of this antibody. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hepatitis A virus (Wikipedia)

LP16708-7   Hepatitis A virus
Hepatitis A virus (HAV) is a small, non-enveloped single-stranded RNA virus that belongs to the Picornaviridae family, genus Hepatovirus. HAV has six genotypes (I to VI) in which genotypes I to III are human isolates and IV to VI are only simian isolates. Genotypes I to III are subdivided into groups A and B. Genotype I is the most frequently reported. PMID: 15914081 The clinical manifestations of HAV infection can vary significantly and range from asymptomatic infection, usually seen in young children, to fulminant hepatitis, which can result in death. HAV has a global distribution, and transmission primarily occurs by the fecal-oral route. The risk of HAV transmission through blood products is very low, but there have been some reports of transmission through plasma products, mainly coagulation factors. PMID: 12186933 PMID: 1318940 Source: Regenstrief LOINC

Fully-Specified Name

Component
Hepatitis A virus RNA
Property
PrThr
Time
Pt
System
Stool
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
HAV RNA Stl Ql NAA+probe
Display Name
HAV RNA NAA+probe Ql (Stl)
Consumer Name Alpha Get Info
Hepatitis A virus (HAV), Stool

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32762-3 Hepatitis A virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-A-Virus RNA:Nachweis oder Schwellenwert:Zeitpunkt:Stuhl:Ordinal:Zielfragmentamplifikation mit Sondendetektion
Synonyms: Hepatovirus A; HAV
el-GR Greek (Greece) Ιός Ηπατίτιδας Α RNA:PrThr:Χρονική στιγμή:Κόπρανα:Τακτική:Ανιχνευτής με ενίσχυση στόχου
Synonyms: HAV
es-ES Spanish (Spain) Virus de la Hepatitis A RNA:PrThr:Punto temporal:Heces:Ord:Sonda con amplificación dirigida
es-MX Spanish (Mexico) ARN del virus de la hepatitis A:Presencia o umbral:Punto temporal:Heces:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Hépatite A virus ARN:Présence/Seuil:Ponctuel:Selle:Qualitatif:PCR amplification de cible
fr-BE French (Belgium) Virus de l'hépatite A ARN:PrThr:Temps ponctuel:Selles:Ordinal:Sonde avec amplification de la cible
Synonyms: HVA
fr-CA French (Canada) Virus de l'hépatite A ARN:Présence-Seuil:Temps ponctuel:Selles:Ordinal:Sonde avec amplification de la cible
it-IT Italian (Italy) Epatite A, virus RNA:PrThr:Pt:Feci:Ord:Sonda.amp.tar
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''epatite A
nl-NL Dutch (Netherlands) Hepatitis A-virus RNA:aanwezigheid:moment:feces:ordinaal:probe-detectie
Synonyms: ontlasting; feces probe.amp.tar
ru-RU Russian (Russian Federation) Гепатита А вирус РНК:PrThr:ТчкВрм:Фекалии:Пор:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR Turkish (Turkey) Hepatit A virüsü RNA:MevcEşik:Zmlı:Dışkı:Srl:Prob.amf.hdf
Synonyms: Gaita; feçes Mevcut
zh-CN Chinese (China) 甲型肝炎病毒 RNA:存在情况或阈值:时间点:大便:序数型:探针法.基因扩增.靶向
Synonyms: A 型 HAV RNA HAV;Hep A;甲型肝炎;甲肝;甲肝病毒;肝炎病毒 A 型 Hep A RNA 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 便;大肠运动;排便;粪便;肠运动 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 甲肝病毒 RNA 经过扩增的 肝 肝炎病毒 A 型 RNA 脱氧核糖核酸探针

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