Version 2.77

Part Description

LP410826-4   Monotypic plasma cell DNA index
DNA index (DI), which is associated with DNA ploidy, is a reflection of the average amount of DNA in the tumor cells. The DI can be measured by flow cytometry or image cytometry, both of which result in a DNA ploidy histogram, where the channel number on the x-axis represents fluorescent intensity or optical density for the two methods, respectively. All cells with the same quantity of DNA form one peak on the histogram, and with a population of normal cells, the largest peak represents diploid cells in G1 of the cell cycle, and a smaller peak represents cells in G2/M-phase. When there is a mixed population of normal and tumor cells, two or more G1 peaks will be seen, one for the normal cells and one or more for the tumor cells. The DI is calculated by dividing the channel number of the tumor cell G1 peak by the channel number of the normal (diploid control) G1 peak. If the tumor cells are diploid, the DI is 1, and if the cells are aneuploid, the DI is greater than or less than 1. For example, tetraploid cells have a DI of 2 because they have twice as much DNA content as normal diploid cells, and hypodiploid tumor cells have a DI of <1. PMID: 24532190 Source: Regenstrief LOINC, PMID: 24532190

Fully-Specified Name

Component
Monotypic plasma cell DNA index
Property
Ratio
Time
Pt
System
Bone mar
Scale
Qn
Method
Flow cytometry

Additional Names

Short Name
Monotypic PC DNA index Mar FC-Rto
Display Name
Monotypic plasma cell DNA index FC (BM) [Ratio]
Consumer Name Alpha Get Info
Monotypic Plasma Cell DNA Index, Bone marrow

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
93363-0 Plasma cell DNA content and proliferation panel - Bone marrow by Flow cytometry (FC)

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Índice de ADN de células plasmáticas monotípicas:Fracción:Punto temporal:Médula ósea:Qn:Citometria de flujo (FC)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Índice de ADN de células plasmáticas monotípicas:Proporción:Punto temporal:Médula ósea:Cuantitativo:Citometría de flujo (FC)
fr-FR French (France) Cellule plasmatique monotypique ADN index:Ratio:Ponctuel:Moelle osseuse:Numérique:Cytométrie de flux
it-IT Italian (Italy) Plasmacellule monotipiche, indice DNA:Rapporto:Pt:Mid oss:Qn:Citometria a flusso
Synonyms: Citometria a flusso (FC) Indice di DNA Indice DNA delle plasmacellule monotipiche Midollo osseo Patologia molecolare Plasmocita Punto nel tempo (episodio)
zh-CN Chinese (China) 单型浆细胞 DNA 指数:比率:时间点:骨髓:定量型:流式细胞测量术
Synonyms: DI;DNA 指数 = 肿瘤 G1 峰的平均通道数（mean channel #）与正常细胞平均通道数之比;DNA 指数（DNA index，DI） 分子病理学;分子病理学试验 动态 单型（单一型）浆细胞 DNA 指数 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 来自于不同体系的两个观察指标之比;比;比值 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 血液制品 - 血浆 骨骼;骨头 髓

Example Units

Unit Source
{ratio} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93360-6