93923-1
ABO and Rh group post transfusion reaction panel - Blood
Active
46270-5 ABO group [Type] in Blood--after transfusion reaction
Part Descriptions
LP17806-8 ABO group
The ABO blood group antigens are encoded by one genetic locus, the ABO locus, which has three alternative forms: A, B, and O. A child receives one of these three forms from each parent, yielding six possible genotypes and four possible blood types (aka phenotypes: A, AB, B, O). ABO blood group antigens remain of prime importance in transfusion and transplantation medicine, and they are the most immunogenic of all the blood group antigens. ABO antibodies are of major clinical significance because they are naturally and universally occurring, and they are highly reactive. The distribution of the four phenotypes varies across the world - type O is the most common, followed by type A, then type B, and type AB is the least common. The ABO system is acknowledged in the pathogenesis of cardiovascular, infectious and neoplastic disorders, and pre-eclampsia. H antigen deficiency is known as the "Bombay phenotype" and is found in 1 in 10,000 people in India and 1 in 1 million people in Europe. [NCBI Books:NBK2267] PMID: 27177402[NCBI Books:NBK2264]
Source: Regenstrief LOINC
LP412149-9 post transfusion reaction BldBk
Investigation of a putative transfusion reaction involves repeat blood typing on the patient's pre-transfusion sample, a sample from the transfused unit, as well as a post-transfusion sample from the patient (where a mixed field pattern suggests that incompatible donor cells were given).
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- ABO group^post transfusion reaction
- Property
- Type
- Time
- Pt
- System
- Bld
- Scale
- Nom
- Method
Additional Names
- Short Name
- ABO Group p transf rx Bld
- Display Name
- ABO group post transfusion reaction (Bld)
- Consumer Name Alpha Get Info
- ABO group after Transfusion Reaction, Blood
Basic Attributes
- Class
- BLDBK
- Type
- Laboratory
- First Released
- Version 2.19
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 17799
Preferred Answer List LL2419-1
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Group A Copyright http://snomed.info/sct ID:112144000 Blood group A (finding) | LA19710-5 | ||
| Group B Copyright http://snomed.info/sct ID:112149005 Blood group B (finding) | LA19709-7 | ||
| Group O Copyright http://snomed.info/sct ID:58460004 Blood group O (finding) | LA19708-9 | ||
| Group AB | LA28449-9 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93923-1 | ABO and Rh group post transfusion reaction panel - Blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Grupos sanguíneos AB0^Reacción pos-transfusional: |
| es-MX | Spanish (Mexico) | Grupo ABO ^ reacción postransfusional: |
| fr-CA | French (Canada) | Groupe ABO^Réaction post-transfusionnelle: |
| fr-BE | French (Belgium) | Groupe ABO^Réaction post-transfusionnelle: Synonyms: Réaction transfusionnelle |
| fr-FR | French (France) | ABO groupage après réaction transfusionnelle: |
| it-IT | Italian (Italy) | ABO, gruppo^reazione post trasfusionale: Synonyms: Banca del sangue dopo trasfusione Gruppo ABO Punto nel tempo (episodio) Reazione trasfusionale Sangue |
| nl-NL | Dutch (Netherlands) | AB0-bloedgroep^na transfusiereactie: |
| pt-BR | Portuguese (Brazil) | Grupo ABO^após reação de transfusão: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | ABO группа^Посттрансфузионная реакция: Synonyms: Кровь Номинальный; |
| tr-TR | Turkish (Turkey) | ABO grubu^snr transfüzyon reaksiyonu: Synonyms: Tür |
| zh-CN | Chinese (China) | ABO 血型^在输血反应之后: Synonyms: React Rxn XXX刺激 - 在...之后 之后于... 之后于输血 之后于输血反应 分类型应答; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
46276-2 Rh [Type] in Blood--after transfusion reaction
Part Descriptions
LP14541-4 Rh
Rh is the most complex of the blood groups systems, encompassing over 45 distinct antigens. The most clinical important antigen, D or Rho, was first described in 1940 and is present in over 85% of the population. Those individuals who lack the D antigen are considered to be Rh negative.
The Rh antigens are encoded by two highly homologous and closely linked genes on the short arm of chromosome 1. The RHD gene codes for the D antigen, or most of its components; RhCE gene codes the Cc and Ee antigens or their variants. The majority of the antigens within this system represent products of gene cross-over, point mutations or deletions within one or both genes.
The Rh antigens appear to be expressed only on red blood cell and they appear early during red cell development. Antibodies against the Rh antigens have caused severe and fatal transfusion reactions and hemolytic disease of the newborn. Rh antigens have been implicated in many diseases such as auto-immune hemolytic anemia, auto-Rh antibodies. Collect: One 4 mL green (sodium or lithium heparin) or serum separator tube. Also acceptable: lavender or pink (EDTA).
Source: Serum, Cells and Rare Fluid Exchange, Rh
LP412149-9 post transfusion reaction BldBk
Investigation of a putative transfusion reaction involves repeat blood typing on the patient's pre-transfusion sample, a sample from the transfused unit, as well as a post-transfusion sample from the patient (where a mixed field pattern suggests that incompatible donor cells were given).
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Rh^post transfusion reaction
- Property
- Type
- Time
- Pt
- System
- Bld
- Scale
- Nom
- Method
Additional Names
- Short Name
- Rh p transf rx Bld
- Display Name
- Rh post transfusion reaction Nom (Bld)
- Consumer Name Alpha Get Info
- Rh after Transfusion Reaction, Blood
Basic Attributes
- Class
- BLDBK
- Type
- Laboratory
- First Released
- Version 2.19
- Last Updated
- Version 2.27
- Order vs. Observation
- Both
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93923-1 | ABO and Rh group post transfusion reaction panel - Blood |
| 93922-3 | Rh antigens and K Ag post transfusion reaction panel - Blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Rh ^ reacción postransfusional: |
| es-ES | Spanish (Spain) | Rh^Reacción pos-transfusional: |
| fr-BE | French (Belgium) | Rh^Réaction post-transfusionnelle: Synonyms: Réaction transfusionnelle |
| fr-FR | French (France) | RH1 (D) antigène après réaction transfusionnelle: |
| fr-CA | French (Canada) | Rh^Réaction post-transfusionnelle: |
| it-IT | Italian (Italy) | Rh^reazione post trasfusionale: Synonyms: Banca del sangue dopo trasfusione Punto nel tempo (episodio) Reazione trasfusionale Sangue |
| nl-NL | Dutch (Netherlands) | Rh^na transfusiereactie: |
| pt-BR | Portuguese (Brazil) | Rh^após reação transfusional: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Rh^Посттрансфузионная реакция: Synonyms: Кровь Номинальный; |
| tr-TR | Turkish (Turkey) | Rh^snr transfüzyon reaksiyonu: Synonyms: Tür |
| zh-CN | Chinese (China) | Rh^在输血反应之后: Synonyms: D 分型; |
90039-9 ABO and Rh group [Type] in Blood--after transfusion reaction
Part Descriptions
LP36683-8 ABO & Rh group
In 1900, Landsteiner observed that the red cells of some individuals were agglutinated by the serum of others and his detailed report a year later heralded the discovery of the first human blood groups. His limited experiments on laboratory colleagues demonstrated three distinct groups; his pupils Von Decastello and Sturli discovered a fourth group in 1902. It was 25 years before these groups were shown to be inherited as Mendelian characters by means of three allelomorphic genes A, B and O and were, in fact, entities of one blood group system. For most of medicine this was considered a meaningless curiosity, but for those involved with the early development of transfusions it was quickly noted that transfusion of blood only of the same group could mean the difference between a successful outcome or a fatality. While various nomenclatures have been used to describe these factors, it was internationally decided in the mid-1940's that the characteristics would be individually identified as A, B, AB and O and the blood group system know as ABO. Since that time there have been billions of tests preformed and almost as many publications describing various aspects and associations of this blood group systems or its allelic products. The genes controlling the ABO system are located on the long arm of chromosome 9 and encode for either an a (1-3) N-acetylgalactosaminyltransferase (for A) or a (1,3) galactosyltransferase (for B). These transferases incorporate immunodominant sugars (GalNAc for A; Gal for B) on to one of four different types of oligosaccharide chains (type 2 is predominant on red cells, type 1 is found in secretions, plasma and some tissue) carried on glycosphingolipid or glycoprotein molecules. The placement of the A and B antigens is dependent upon the existence of a substrate produced by the Hh blood group system (ISBT # 018). Some individuals have weakened or variant expression of A and/or B which can be attributed to inheritance of variant forms of transferases. Those individuals that have neither transferases, inheritors of two amorph genes, are group O. To date, 14 A alleles, 14 B alleles and 8 O alleles have been identified at the molecular level and more remain to be found. The ABO antigens, as stated above are not restricted to the red blood cell membrane but can be found in saliva and all body fluids except spinal fluid if the individual has inherited a secretor gene. The antigens are also found on most epithelial and endothelial cells. It also appears on lymphocytes and platelets as it is adsorbed from the plasma. Alterations of ABH expression have been found in various forms of cancer. Furthermore, antigens of the ABO system may play a role in resistance to bacteria or viruses.
Source: Serum, Cells and Rare Fluid Exchange, ABO & Rh
LP412149-9 post transfusion reaction BldBk
Investigation of a putative transfusion reaction involves repeat blood typing on the patient's pre-transfusion sample, a sample from the transfused unit, as well as a post-transfusion sample from the patient (where a mixed field pattern suggests that incompatible donor cells were given).
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- ABO & Rh group^post transfusion reaction
- Property
- Type
- Time
- Pt
- System
- Bld
- Scale
- Nom
- Method
Additional Names
- Short Name
- ABO + Rh p transf rx Bld
- Display Name
- ABO and Rh group post transfusion reaction (Bld)
- Consumer Name Alpha Get Info
- ABO and Rh group after Transfusion Reaction, Blood
Basic Attributes
- Class
- BLDBK
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.72
- Order vs. Observation
- Both
Preferred Answer List LL2972-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| O Pos Copyright http://snomed.info/sct ID:278147001 Blood group O Rh(D) positive (finding) | LA21321-7 | ||
| O Neg Copyright http://snomed.info/sct ID:278148006 Blood group O Rh(D) negative (finding) | LA21322-5 | ||
| B Pos Copyright http://snomed.info/sct ID:278150003 Blood group B Rh(D) positive (finding) | LA21327-4 | ||
| B Neg Copyright http://snomed.info/sct ID:278153001 Blood group B Rh(D) negative (finding) | LA21328-2 | ||
| AB Pos Copyright http://snomed.info/sct ID:278151004 Blood group AB Rh(D) positive (finding) | LA21323-3 | ||
| AB Neg Copyright http://snomed.info/sct ID:278154007 Blood group AB Rh(D) negative (finding) | LA21324-1 | ||
| A Pos Copyright http://snomed.info/sct ID:278149003 Blood group A Rh(D) positive (finding) | LA21325-8 | ||
| A Neg Copyright http://snomed.info/sct ID:278152006 Blood group A Rh(D) negative (finding) | LA21326-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 93923-1 | ABO and Rh group post transfusion reaction panel - Blood |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | ABO y grupo Rh ^ reacción postransfusional: |
| es-ES | Spanish (Spain) | Grupo ABO y Rh^Reacción pos-transfusional: Synonyms: Grupos sanguíneos AB0 y Rh |
| fr-FR | French (France) | ABO et RHD groupage après réaction transfusionnelle: |
| fr-CA | French (Canada) | Groupe ABO & Rh^Réaction post-transfusionnelle: |
| it-IT | Italian (Italy) | ABO & Rh, gruppo^reazione post trasfusionale: Synonyms: Banca del sangue dopo trasfusione Gruppo ABO & |
| nl-NL | Dutch (Netherlands) | AB0 & Rh-bloedgroep^na transfusiereactie: |
| ru-RU | Russian (Russian Federation) | ABO & Rh^Посттрансфузионная реакция: Synonyms: Кровь Номинальный; |
| tr-TR | Turkish (Turkey) | ABO ve Rh^snr transfüzyon reaksiyonu: Synonyms: Tür |
| zh-CN | Chinese (China) | ABO与Rh血型^在输血反应之后: Synonyms: ABO & |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.