Version 2.78

Term Description

This panel contains results for the detection of Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), initially known as 2019-Novel Coronavirus (2019-nCoV), in various specimens, including respiratory and serum, using nucleic acid amplification assays with probe-based detection for the diagnosis of Coronavirus Disease 2019 (COVID-19). Various assays have been developed that contain primer-probe sets targeting regions of the SARS-CoV-2 genome, including regions in the RdRp, N, and E genes. [https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] The CDC-developed SARS-CoV-2 assay contains primer and probe sets designed for specific detection of SARS-CoV-2 (N1 and N2 assays) as well as detection of the SARS-like coronaviruses (N3 assay).[CDC: coronavirus/2019-nCoV/lab/]
Source: Regenstrief LOINC

Part Description

LP417539-6   SARS coronavirus 2 RNA panel
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type Source Reference
Package Insert Centers for Disease Control and Prevention This document describes the use of real-time RT PCR (rRT-PCR) assays for the in vitro qualitative detection of 2019-Novel Coronavirus (2019-nCoV) in respiratory specimens and sera. The 2019-nCoV primer and probe sets are designed for the universal detection of SARS-like coronaviruses (N3 assay) and for specific detection of 2019-nCoV (N1 and N2 assays). Real-Time RT-PCR Panel for Detection 2019-Novel Coronavirus
Package Insert World Health Organization (WHO)Copyright Copyright © 2001 World Health Organization. Diagnostic detection of 2019-nCoV by real-time RT-PCR

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
94306-8 SARS-CoV-2 (COVID-19) RNA panel - Specimen by NAA with probe detection
Indent94312-6 SARS-CoV-2 (COVID-19) N gene [Cycle Threshold #] in Specimen by Nucleic acid amplification using CDC primer-probe set N2 {Ct_value}
Indent94311-8 SARS-CoV-2 (COVID-19) N gene [Cycle Threshold #] in Specimen by Nucleic acid amplification using CDC primer-probe set N1 {Ct_value}
Indent94510-5 SARS-CoV-2 (COVID-19) N gene [Cycle Threshold #] in Specimen by NAA with probe detection {Ct_value}
Indent94308-4 SARS-CoV-2 (COVID-19) N gene [Presence] in Specimen by Nucleic acid amplification using CDC primer-probe set N2
Indent94316-7 SARS-CoV-2 (COVID-19) N gene [Presence] in Specimen by NAA with probe detection
Indent94307-6 SARS-CoV-2 (COVID-19) N gene [Presence] in Specimen by Nucleic acid amplification using CDC primer-probe set N1
Indent94511-3 SARS-CoV-2 (COVID-19) ORF1ab region [Cycle Threshold #] in Specimen by NAA with probe detection {Ct_value}
Indent94639-2 SARS-CoV-2 (COVID-19) ORF1ab region [Presence] in Specimen by NAA with probe detection
Indent94314-2 SARS-CoV-2 (COVID-19) RdRp gene [Presence] in Specimen by NAA with probe detection
Indent94645-9 SARS-CoV-2 (COVID-19) RdRp gene [Cycle Threshold #] in Specimen by NAA with probe detection {Ct_value}
Indent94643-4 SARS-CoV-2 (COVID-19) S gene [Cycle Threshold #] in Specimen by NAA with probe detection {Ct_value}
Indent94641-8 SARS-CoV-2 (COVID-19) S gene [Presence] in Specimen by NAA with probe detection
Indent94309-2 SARS-CoV-2 (COVID-19) RNA [Presence] in Specimen by NAA with probe detection
Indent94746-5 SARS-CoV-2 (COVID-19) RNA [Cycle Threshold #] in Specimen by NAA with probe detection {Ct_value}
Indent94819-0 SARS-CoV-2 (COVID-19) RNA [Log #/volume] (viral load) in Specimen by NAA with probe detection {Log_copies}/mL
Indent94315-9 SARS-related coronavirus E gene [Presence] in Specimen by NAA with probe detection
Indent94509-7 SARS-related coronavirus E gene [Cycle Threshold #] in Specimen by NAA with probe detection {Ct_value}
Indent94647-5 SARS-related coronavirus RNA [Presence] in Specimen by NAA with probe detection
Indent94313-4 SARS-related coronavirus N gene [Cycle Threshold #] in Specimen by Nucleic acid amplification using CDC primer-probe set N3 {Ct_value}
Indent94310-0 SARS-related coronavirus N gene [Presence] in Specimen by Nucleic acid amplification using CDC primer-probe set N3

Fully-Specified Name

Component
SARS coronavirus 2 RNA panel
Property
-
Time
Pt
System
XXX
Scale
-
Method
Probe.amp.tar

Additional Names

Short Name
SARS-CoV-2 RNA Pnl Spec NAA+probe
Display Name
SARS-CoV-2 (COVID-19) RNA panel NAA+probe (Specimen)
Consumer Name Alpha Get Info
SARS-CoV-2 (COVID-19) RNA Panel, Specimen

Ask at Order Entry

81959-9 Public health laboratory ask at order entry panel

This panel contains a convenience grouping of terms for questions commonly asked when an order is placed in a public health laboratory.

LOINC Name R/O/C Cardinality Example UCUM Units
81959-9 Public health laboratory ask at order entry panel
Indent81744-5 Submitter's laboratory test method [Type] in Specimen
Indent81658-7 Suspected organism [Identifier] in Specimen
Indent86952-9 Preliminary testing done Specimen
Indent86953-7 Preliminary testing result Specimen
Indent86955-2 Preliminary testing affected submission for further testing Specimen
Indent95417-2 Whether this is the patient's first test for condition of interest
Indent95418-0 Whether patient is employed in a healthcare setting
Indent95419-8 Whether the patient has symptoms related to condition of interest
Indent11368-8 Illness or injury onset date and time C
Indent77974-4 Whether the patient was hospitalized for condition of interest
Indent95420-6 Whether the patient was admitted to intensive care unit (ICU) for condition of interest
Indent95421-4 Whether patient resides in a congregate care setting
Indent82810-3 Pregnancy status C
Indent30525-0 Age a

Basic Attributes

Class
PANEL.MICRO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.69
Order vs. Observation
Order
Panel Type
Panel

Member of these Groups Get Info

LOINC Group Group Name
LG51017-8 SARSCoV2 detection
LG51019-4 SARSCoV2 molecular detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) SARS-Coronavirus 2 RNA (Liste):-:Zeitpunkt:XXX:-:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) Panel de ARN del SARS-CoV-2 (COVID-19):Propiedades mixtas (sólo paneles):Punto temporal:XXX:-:Sonda con amplificación dirigida
es-MX Spanish (Mexico) Panel de ARN del coronavirus 2 del SARS:-:Punto temporal:XXX:-:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Coronavirus SARS-CoV-2 ARN panel:-:Ponctuel:Milieux divers:-:PCR amplification de cible
fr-CA French (Canada) Coronavirus 2 du SRAS, ARN panel:-:Temps ponctuel:XXX:-:Sonde avec amplification de la cible
it-IT Italian (Italy) SARS coronavirus 2, panel RNA:-:Pt:XXX:-:Sonda.amp.tar
Synonyms: Coronavirus della SARS Microbiologia Panel RNA di SARS-CoV-2 (COVID-19) Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Set di prescrizione microbiologia Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) SARS-CoV-2 RNA panel:-:moment:XXX:-:probe-detectie
Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19
zh-CN Chinese (China) SARS 冠状病毒 2 RNA 组套:-:时间点:XXX:-:探针法.基因扩增.靶向
Synonyms: 2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 Ⅱ II SARS 冠状病毒 2 RNA 组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;2019 新型冠状病毒;2019 年新型冠状病毒;2019-nCoV;SARS-CoV-2;新型冠状病毒肺炎;新冠肺炎;Coronavirus disease 2019;COVID-19;冠状病毒疾病2019;严重急性呼吸综合征;severe acute respiratory syndrome;SARS;传染性非典型肺炎;infectious atypical pneumonia;非典 SARS;SARS 病毒;SARS-CoV;严重急性呼吸综合征;严重急性呼吸综合征病毒;萨斯病毒;非典;非典型肺炎;非典型肺炎病毒;非典病毒 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.微生物学;实验室组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）类.微生物学试验;医嘱组.微生物学试验;医嘱组类.微生物学;医嘱组类.微生物学试验;实验室医嘱组类.微生物学;微生物学医嘱组;微生物学医嘱组类 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 组 组合 组合医嘱 组合类 组套 经过扩增的 脱氧核糖核酸探针

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94306-8
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/94306-8