96073-2
HEDIS MY 2020 Value Set - FIT-DNA
Discouraged
77353-1 Noninvasive colorectal cancer DNA and occult blood screening [Interpretation] in Stool Narrative
Term Description
This term was created for, but is not limited in use to, Exact Sciences' Cologuard DNA screening test for colorectal cancer. The Cologuard algorithm includes two laboratory procedures performed on a single stool specimen: 1) detection and quantification of fecal occult blood using ELISA; and 2) detection of multiple genetic biomarkers (NDRG4 and BMP3 methylation targets, seven KRAS point mutations, and beta actin as a proxy for the total amount of human DNA in each sample) using magnetic bead based oligonucleotide hybrid capture to isolate the biomarkers followed by quantitative real-time target and signal amplification. The occult blood and genetic biomarker results are subsequently entered into a logistic regression model, and the results from this model are used to calculate a composite score from which the final binary result (positive, negative) is determined. PMID: 24645800
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Noninvasive colorectal cancer DNA+occult blood screening
- Property
- Imp
- Time
- Pt
- System
- Stool
- Scale
- Nar
- Method
Additional Names
- Short Name
- Noninv colon ca DNA+occ bld scrn Stl-Imp
- Display Name
- Noninvasive colorectal cancer DNA and occult blood screening Nar (Stl) [Interp]
- Consumer Name Alpha Get Info
- Interpretation of Noninvasive Colorectal Cancer DNA and Occult Blood Screening test result, Stool
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.52
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 4228
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 82955-6 | HEDIS 2017 Value Sets |
| 87625-0 | HEDIS 2018 Value Sets |
| 90766-7 | HEDIS 2019 Value Sets |
| 94137-7 | HEDIS 2020 Value Sets |
| 96068-2 | HEDIS MY 2020 Value Sets |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Screening no invasivo de cancer colorectal ADN+sangre oculta: |
| es-MX | Spanish (Mexico) | Análisis de ADN + sangre oculta de cáncer colorrectal no invasivo: |
| fr-FR | French (France) | Cancer colorectal non invasif ADN+sang occulte dépistage: |
| it-IT | Italian (Italy) | Screening non invasivo DNA+sangue occulto tumore colorettale: Synonyms: Impressione/interpretazione di studio Patologia molecolare Punto nel tempo (episodio) Screening non invasivo DNA e sangue occulto per di |
| tr-TR | Turkish (Turkey) | Noninvaziv kolorektal kanser DNA+gaitada gizli kan tarama: Synonyms: Gaita; |
| zh-CN | Chinese (China) | 无创性结直肠癌 DNA+潜血筛查: Synonyms: Asympt SCN 便; |
77354-9 Noninvasive colorectal cancer DNA and occult blood screening [Presence] in Stool
Term Description
This term was created for, but is not limited in use to, Exact Sciences' Cologuard DNA screening test for colorectal cancer. The Cologuard algorithm includes two laboratory procedures performed on a single stool specimen: 1) detection and quantification of fecal occult blood using ELISA; and 2) detection of multiple genetic biomarkers (NDRG4 and BMP3 methylation targets, seven KRAS point mutations, and beta actin as a proxy for the total amount of human DNA in each sample) using magnetic bead based oligonucleotide hybrid capture to isolate the biomarkers followed by quantitative real-time target and signal amplification. The occult blood and genetic biomarker results are subsequently entered into a logistic regression model, and the results from this model are used to calculate a composite score from which the final binary result (positive, negative) is determined. PMID: 24645800
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Noninvasive colorectal cancer DNA+occult blood screening
- Property
- PrThr
- Time
- Pt
- System
- Stool
- Scale
- Ord
- Method
Additional Names
- Short Name
- Noninv colon ca DNA+occ bld scrn Stl Ql
- Display Name
- Noninvasive colorectal cancer DNA and occult blood screening Ql (Stl)
- Consumer Name Alpha Get Info
- Noninvasive Colorectal Cancer DNA and Occult Blood Screening, Stool
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.52
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 2032
Example Answer List LL3293-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Sample could not be processed | LA22772-0 | ||
| No result obtained | LA22773-8 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 82955-6 | HEDIS 2017 Value Sets |
| 87625-0 | HEDIS 2018 Value Sets |
| 90766-7 | HEDIS 2019 Value Sets |
| 94137-7 | HEDIS 2020 Value Sets |
| 96068-2 | HEDIS MY 2020 Value Sets |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Screening no invasivo de cancer colorectal ADN+sangre oculta: |
| es-MX | Spanish (Mexico) | Análisis de ADN + sangre oculta de cáncer colorrectal no invasivo: |
| fr-FR | French (France) | Cancer colorectal non invasif ADN+sang occulte dépistage: |
| it-IT | Italian (Italy) | Screening non invasivo DNA+sangue occulto tumore colorettale: Synonyms: Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Screening non invasivo DNA e sangue occulto per di |
| tr-TR | Turkish (Turkey) | Noninvaziv kolorektal kanser DNA+gaitada gizli kan tarama: Synonyms: Gaita; |
| zh-CN | Chinese (China) | 无创性结直肠癌 DNA+潜血筛查: Synonyms: Asympt SCN 依次型; |
Third Party Copyright
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