96451-0
Alpha-1-Fetoprotein and Alpha-1-Fetoprotein.L3 panel - Serum or Plasma
Active
1834-1 Alpha-1-Fetoprotein [Mass/volume] in Serum or Plasma
Part Descriptions
LP14331-0 Alpha-1-Fetoprotein
Alpha-1-fetoprotein (AFP) is a key variable in prenatal screening for the detection of trisomy 18, 21 and neural tube defect. It is also the primary tumor marker for nonseminomatous testicular cancers. Post-operative AFP levels that remain above normal imply residual tumor, and/or tumor recurrence. AFP can be high in up to 70% of patients with primary hepatocellular carcinoma. Elevated AFP levels have occasionally been found in association with gastrointestinal tract cancers.
Serum AFP is also elevated in ataxia telangiectasia, hereditary tyrosinemia, teratocarcinoma, and non-cancerous hepatic conditions, such as acute viral hepatitis, chronic active hepatitis and cirrhosis. Elevation of serum AFP in non-cancerous hepatic diseases is usually transient.
Source: Regenstrief Institute
Fully-Specified Name
- Component
- Alpha-1-Fetoprotein
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- AFP SerPl-mCnc
- Display Name
- AFP [Mass/Vol]
- Consumer Name Alpha Get Info
- Alpha-fetoprotein, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 502
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 96451-0 | Alpha-1-Fetoprotein and Alpha-1-Fetoprotein.L3 panel - Serum or Plasma |
| 48802-3 | Alpha-1-Fetoprotein panel - Serum or Plasma |
| 49085-4 | First and Second trimester integrated maternal screen panel |
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
| 96452-8 | Hepatocellular carcinoma risk panel - Serum or Plasma |
| 48799-1 | Second trimester penta maternal screen panel - Serum or Plasma |
| 48800-7 | Second trimester quad maternal screen panel - Serum or Plasma |
| 35086-8 | Second trimester triple maternal screen panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG5597-2 | Alpha-1-Fetoprotein| |
| LG42656-5 | Alpha-1-Fetoprotein| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Alpha-Fetoprotein |
| de-DE | German (Germany) | Alpha-1-Fetoprotein: Synonyms: AFP |
| el-GR | Greek (Greece) | α1-εμβρυϊκή πρωτεΐνη: |
| es-AR | Spanish (Argentina) | alfa-1-fetoproteína: |
| es-ES | Spanish (Spain) | Alfa-1-Fetoproteina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Alfa-1-fetoproteína: |
| et-EE | Estonian (Estonia) | Alfafetoproteiin: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Alpha-1-foetoprotéine: |
| fr-BE | French (Belgium) | Alpha-1-foetoprotéine: Synonyms: AFP |
| fr-FR | French (France) | Alpha-1-foetoprotéine: |
| it-IT | Italian (Italy) | Alfa-1-Fetoproteina: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 알파-1-태아단백: |
| nl-NL | Dutch (Netherlands) | alfa-1-foetoproteïne: |
| pt-BR | Portuguese (Brazil) | Alfa-1-Fetoproteína: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Альфа-1-фетопротеин: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Alfa-1-Fetoprotein: |
| uk-UA | Ukrainian (Ukraine) | Альфа-1-Фетопротеїн: Synonyms: A1; |
| zh-CN | Chinese (China) | Alpha-1-胎儿球蛋白: Synonyms: Ⅰ A1 型 A1 胎儿球蛋白; |
Example Units
| Unit | Source |
|---|---|
| ng/mL | Example UCUM Units |
| ug/L | eCHN |
42332-7 Alpha-1-Fetoprotein L3/Alpha-1-fetoprotein.total in Serum or Plasma
Part Descriptions
LP36040-1 Alpha-1-Fetoprotein.L3
In oncology, AFP-L3 is an isoform of Alpha-fetoprotein (AFP), a substance typically used in the triple test during pregnancy and for screening chronic liver disease patients for hepatocellular carcinoma (HCC). AFP can be fractionated by affinity electrophoresis into 3 glycoforms: L1, L2, and L3 based on the reactivity with the lectin Lens culinaris agglutinin (LCA). AFP-L3 binds strongly to LCA via an additional α 1-6 fucose residue attached at the reducing terminus of N-acetylglucosamine; this is in contrast to the L1 isoform. It is the L1 isoform which is typically associated with non-HCC inflammation of liver disease condition. The L3 isoform is specific to malignant tumors and its detected presence can serve to identify patients whom need increased monitoring for the development of HCC in high risk populations (i.e. chronic hepatitis B & C and/or liver cirrhosis). AFP-L3% is now being considered as a tumor marker for the North American demographic.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- Alpha-1-Fetoprotein.L3/Alpha-1-Fetoprotein.total
- Property
- MFr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- AFP L3 MFr SerPl
- Display Name
- AFP L3/Total AFP [Mass fraction]
- Consumer Name Alpha Get Info
- Alpha-fetoprotein L3/Total Alpha-1-fetoprotein, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.16
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4468
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 96451-0 | Alpha-1-Fetoprotein and Alpha-1-Fetoprotein.L3 panel - Serum or Plasma |
| 96452-8 | Hepatocellular carcinoma risk panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Alfa-1-Fetoproteína.L3 / Alfa-1-Fetoproteína.total: |
| es-ES | Spanish (Spain) | Alfa-1-fetoproteina L3/Alfa-1-fetoproteina.total: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Alfa-1-fetoproteiin.L3/alfa-1-fetoproteiin.üld: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-BE | French (Belgium) | Alpha-1-foetoprotéine.L3/Alpha-1-foetoprotéine.totale: Synonyms: AFP |
| fr-CA | French (Canada) | Alpha-1-foetoprotéine.L3/Alpha-1-foetoprotéine.totale: |
| fr-FR | French (France) | Alpha-1-foetoprotéine L3/alpha-1-foetoprotéine totale: |
| it-IT | Italian (Italy) | Alfa-1-Fetoproteina L3/Alfa-1-fetoproteina.totale: Synonyms: Alfa-1-Fetoproteina L3 Chimica Frazione di massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 알파-1-태아단백.L3/총알파-1-태아단백: |
| nl-NL | Dutch (Netherlands) | alfa-1-foetoproteïne.L3/alfa-1-foetoproteïne.totaal: |
| pt-BR | Portuguese (Brazil) | Alfa-1-Fetoproteína.L3/Alfa-1-Fetoproteína.total: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Альфа-1-Фетопротеин.L3/Альфа-1-фетопротеин.общий: Synonyms: Количественный Массовая доля Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Alfa-1-Fetoprotein.L3/Alfa-1-fetoprotein.total: |
| zh-CN | Chinese (China) | Alpha-1-胎儿球蛋白.L3/Alpha-1-胎儿球蛋白.总计: Synonyms: Ⅰ A1 型 A1 胎儿球蛋白 L3; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
| % | REGENSTRIEF |
69048-7 Immunologist review of results
Fully-Specified Name
- Component
- Immunologist review
- Property
- Imp
- Time
- Pt
- System
- XXX
- Scale
- Nar
- Method
Additional Names
- Short Name
- Immunologist review
- Display Name
- Immunologist review [Interp]
- Consumer Name Alpha Get Info
- Immunologist review of test result
Basic Attributes
- Class
- MISC
- Type
- Laboratory
- First Released
- Version 2.38
- Last Updated
- Version 2.75
- Change Reason
- Release 2.75: ORDER_OBS: submitter requested change;
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4075
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 96451-0 | Alpha-1-Fetoprotein and Alpha-1-Fetoprotein.L3 panel - Serum or Plasma |
| 90414-4 | B-cell phenotyping panel - Blood |
| 103575-7 | Cat epithelium IgE panel - Serum or Plasma |
| 102085-8 | CNS Demyelinating Disease Panel - Serum or Plasma by Flow cytometry (FC) |
| 104134-2 | Dementia evaluation panel - Cerebral spinal fluid |
| 104595-4 | Dengue virus Ab.IgG and IgM and NS1 Ag panel - Serum or Plasma |
| 104673-9 | Diabetes mellitus type 1 autoimmune panel - Serum or Plasma |
| 103574-0 | Dog dander IgE panel - Serum or Plasma |
| 96452-8 | Hepatocellular carcinoma risk panel - Serum or Plasma |
| 90416-9 | Lymphocyte subset and B-cell phenotyping panel - Blood |
| 101416-6 | Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid |
| 101417-4 | Pediatric autoimmune central nervous system disorders evaluation panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Komm.Auto.AK |
| es-MX | Spanish (Mexico) | Revisión de inmunólogo: |
| es-ES | Spanish (Spain) | Revisión del inmunólogo: |
| fr-FR | French (France) | Validation des résultats d'immunologie: |
| it-IT | Italian (Italy) | Immunologo, esame: Synonyms: Esame di immunologo Impressione/interpretazione di studio Miscellanea Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | beoordeling door immunoloog: |
| ru-RU | Russian (Russian Federation) | Иммунолог рецензия: Synonyms: Впечатление/интерпретация исследования Описательный Точка во времени; |
| tr-TR | Turkish (Turkey) | İmmünolog değerlendirmesi: |
| zh-CN | Chinese (China) | 免疫学家审核: Synonyms: 不明的; |