97097-0 SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

Term Description

Qualitative detection of SARS coronavirus 2 (SARS-CoV-2) antigen in upper respiratory specimens, such as nasopharyngeal swabs, by rapid immunoassay methods. Testing is performed for the diagnosis of Coronavirus Disease 2019 (COVID-19).
Source: Regenstrief LOINC

Part Descriptions

LP417540-4   SARS coronavirus 2
The 2019 Novel Coronavirus (2019-nCoV) is a coronavirus first identified as the cause of a respiratory illness outbreak in Wuhan, China. Initially, the outbreak was linked to a large seafood and animal market and thought to only be spread by animal to person contact. Within a short time, a growing number of patients who had not been exposed to animal markets were diagnosed with the infection, indicating person-to-person transmission. As of January 2020, infections with 2019-nCoV had been reported internationally due to confirmed cases in travelers from Wuhan. Overall, clinical symptoms appear milder than SARS Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome (MERS) Coronavirus (MERS-CoV) infections as do the fatality rate and transmissibility. PMID: 31953166 Reported illnesses range from minor or no respiratory symptoms to severe acute respiratory illness and death.

The full genome of the 2019-nCoV was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Source: LOINC

Reference Information

Fully-Specified Name

Component

SARS coronavirus 2 Ag

Property

PrThr

Time

Pt

System

Respiratory system specimen.upper

Scale

Ord

Method

IA.rapid

Additional Names

Short Name

SARS-CoV-2 Ag Upper resp Ql IA.rapid

Display Name

SARS-CoV-2 (COVID-19) Ag IA.rapid Ql (Upper resp)

Consumer Name Alpha Get Info

SARS-CoV-2 (COVID-19) antigen, Upper respiratory

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.70

Last Updated

Version 2.77

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC;

Order vs. Observation

Both

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 2019 Novel Coronavirus
• 2019-nCoV
• Antigen
• Antigens
• Breathing
• Corona virus
• COVID19
• COVID-19
• EIA
• ELFA
• ELISA
• Enzyme immunoassay
• IAA
• ID
• II
• Infectious Disease
• InfectiousDisease
• Lungs
• MEIA
• Microbiology
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• RS
• SARS Coronavirus 1
• SARS-CoV
• SARS-CoV-1
• SARS-CoV-2
• Screen
• Severe Acute Respiratory Syndrome
• Spec
• SUDS
• Up
• Upper resp
• Viral Pneumonias
• Wuhan coronavirus

80383-3 Influenza virus B Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

Term Description

This term was created for, but is not limited in use to, the Influenza B part of the bioMerieux bioNexia Influenza A+B test, which is intended for the qualitative detection and differentiation of Influenza type A and type B antigens in human nasopharyngeal samples. The results of the bioNexia assay should be read ten minutes after the sample is applied to the sample well.
Source: Regenstrief LOINC

Part Descriptions

LP14240-3   Influenza virus B
Influenza virus from the family Orthomyxoviridae are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C viruses are medically relevant to humans. Influenza A and B viruses have a similar structure whereby these viruses each contain eight discrete single-stranded RNA gene segments, each encoding at least one protein. While having a close phylogenetic relationship, influenza virus types A and B manifest very differently. While IAV infects birds, humans and other mammals, influenza B only infects humans and seals. Although both viruses cause human respiratory infection seasonally in temperate climate regions and more continually in the tropics, influenza B is normally less prevalent and causes less severe disease than IAV viruses. Research is ongoing to determine the evolutionary and epidemiological factors that shape the genetic diversity of influenza B virus. PMID: 25812763 [CDC:flu/about/viruses/types] Source: Regenstrief LOINC

Fully-Specified Name

Component

Influenza virus B Ag

Property

PrThr

Time

Pt

System

Respiratory system specimen.upper

Scale

Ord

Method

IA.rapid

Additional Names

Short Name

FLUBV Ag Upper resp Ql IA.rapid

Display Name

FLUBV Ag IA.rapid Ql (Upper resp)

Consumer Name Alpha Get Info

Influenza B (Flu B) antigen, Upper respiratory

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.54

Last Updated

Version 2.77

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC; Release 2.70: SYSTEM: Updated from "Nph" to make the LOINC term consistent with the original intent to represent a manufacturer's test covering NPH washes and nose swabs, as well as to make it consistent across panel usage.; Previous Releases: Corrected System from "Nasopharynx", which is used for LOINC clinical terms, to "Nph", which is the form used for LOINC lab terms.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

1305

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Antigen
• Antigens
• Breathing
• EIA
• ELFA
• ELISA
• Enzyme immunoassay
• FLUB
• FLUBV
• FLUV
• IAA
• ID
• Infectious Disease
• InfectiousDisease
• Influ
• Influenza B
• Influenza B virus
• Lungs
• MEIA
• Microbiology
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• RS
• Screen
• Spec
• SUDS
• Up
• Upper resp

80382-5 Influenza virus A Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

Term Description

This term was created for, but is not limited in use to, the Influenza A part of the bioMerieux bioNexia Influenza A+B test, which is intended for the qualitative detection and differentiation of Influenza type A and type B antigens in human nasopharyngeal samples. The results of the bioNexia assay should be read ten minutes after the sample is applied to the sample well.
Source: Regenstrief LOINC

Part Descriptions

LP14239-5   Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

Fully-Specified Name

Component

Influenza virus A Ag

Property

PrThr

Time

Pt

System

Respiratory system specimen.upper

Scale

Ord

Method

IA.rapid

Additional Names

Short Name

FLUAV Ag Upper resp Ql IA.rapid

Display Name

FLUAV Ag IA.rapid Ql (Upper resp)

Consumer Name Alpha Get Info

Influenza A (Flu A) antigen, Upper respiratory

Basic Attributes

Class

MICRO

Type

Laboratory

First Released

Version 2.54

Last Updated

Version 2.77

Change Reason

Release 2.77: SYSTEM: Updated to standardize the representation of "Respiratory system specimen" in the System subhierarchy across LOINC; Release 2.70: SYSTEM: Updated from "Nph" to make the LOINC term consistent with the original intent to represent a manufacturer's test covering NPH washes and nose swabs, as well as to make it consistent across panel usage.; Previous Releases: Corrected System from "Nasopharynx", which is used for LOINC clinical terms, to "Nph", which is the form used for LOINC lab terms.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.

Order vs. Observation

Both

Common Test Rank Get Info

1303

Example Answer List LL744-4

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• Antigen
• Antigens
• Avian influenza
• Bird flu
• Breathing
• EIA
• ELFA
• ELISA
• Enzyme immunoassay
• FLUA
• FLUAV
• FLUV
• Fowl plague
• IAA
• ID
• Infectious Disease
• InfectiousDisease
• Influ
• Influenza A
• Influenza A virus
• Lungs
• MEIA
• Microbiology
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• RS
• Screen
• Spec
• SUDS
• Up
• Upper resp