Version 2.80

Descriptions

An enzyme hydrolyzing terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES. Hexosaminidase A cleaves GM2, GA2, globosides, and hexosamine oligosaccharides. Hexosaminidase B cleaves all the above substrates except GM2. Deficiency of Hexosaminidase A causes TAY-SACHS DISEASE, while deficiency of both A and B isozymes causes SANDHOFF DISEASE. The enzyme has also been used as a tumor marker to distinguish between malignant and benign disease. Source: National Library of Medicine, MeSH 2006

Beta-N-acetylhexosaminidase is also known as hexosaminidase and has two forms, A and B. Hexosaminidase B is used to screen for Tay-Sachs disease. Source: Regenstrief Institute

Basic Part Properties

Part Name
Beta-N-acetylhexosaminidase
Part Display Name
Beta-N-acetylhexosaminidase
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
B-NAH

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP14022-5

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) Beta-N-乙酰己糖胺酶
Synonyms: Beta-N-乙酰氨基己糖苷酶;B-NAH;GM2-神经节苷脂沉积症;GM2-神经节苷脂贮积病;β-N-乙酰己糖胺酶;β-N-乙酰氨基己糖苷酶;己糖胺酶;氨基己糖苷酶
es-ES Spanish (Spain) Beta-N-acetilhexosaminidasa
it-IT Italian (Italy) Beta-N-acetilesosaminidasi
et-EE Estonian (Estonia) Beeta-N-atsetüülheksosaminidaas
tr-TR Turkish (Turkey) Beta-N-asetilhekzosaminidaz
ru-RU Russian (Russian Federation) Бета-N-ацетилгексозаминидаза
fr-BE French (Belgium) Béta-N-acétylhexosaminidase
fr-CA French (Canada) Bêta-N-acétylhexosaminidase
nl-NL Dutch (Netherlands) bèta-N-acetylhexosaminidase
Synonyms: Beta-N-acetylhexosaminidase
el-GR Greek (Greece) β-N-ακετυλοεξοζαμινιδάση
Synonyms: β-N-ακετυλοεξοζαμινιδάση