LP14988-7
Demeclocycline
Active
Descriptions
Demeclocycline (marketed as Declomycin®, Declostatin® and Ledermycin®) is a member of the tetracycline antibiotics group used in various types of bacterial infections. One of its other registered uses is the treatment of hyponatremia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective. It is derived from the Streptomyces aureofaciens fungal strain. Mode of action:Its use as an antibiotic is particularly in Lyme disease, acne and bronchitis. Resistance is gradually becoming more common. As with related tetracycline antibiotics, demeclocycline acts by binding to the 30S- and 50S-RNA, which impairs protein synthesis by bacteria. It is therefore bacteriostatic (it impairs bacterial growth but does not kill bacteria directly). Demeclocycline is rarely used for infections. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Demeclocycline (Wikipedia)
A TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time. Source: National Library of Medicine, MeSH 2006
Basic Part Properties
- Part Display Name
- Demeclocycline
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Demeclocycline
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Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 去甲金霉素 Synonyms: 脱甲四环素 |
fr-CA | French (Canada) | Déméclocycline |
et-EE | Estonian (Estonia) | Demeklotsükliin |
es-ES | Spanish (Spain) | Demeclociclina |
it-IT | Italian (Italy) | Demeclociclina |
tr-TR | Turkish (Turkey) | Demeclosiklin |
ru-RU | Russian (Russian Federation) | Демеклоциклин |
nl-NL | Dutch (Netherlands) | demeclocycline |
fr-BE | French (Belgium) | Déméclocycline |
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