LP15030-7
Immunoglobulin light chains.kappa
Active
Description
All immunoglobulins contain two polypeptide chains: a long (heavy) and a short (light) chain. The two chains interact via disulfide bonds. There are two types of light chains, named kappa and lambda. Serum free light chain (SFLC) testing, a kappa/lambda ratio and a protein electrophoresis test are done to help detect, diagnose and monitor plasma cell disorders (dyscrasias) including multiple myeloma and primary amyloidosis. Normal readings are seen when there is a kappa/lambda ratio of approximately 0.26 to 1.65 and free light chains are present in the blood at low levels. Increased kappa free light chains and an increased kappa/lambda ratio are present with plasma cell disorders that produce excess monoclonal kappa light chains. The tests can also be used to monitor response to treatment. An increase in serum free light chains along with an abnormal kappa/lambda ratio may indicate primary amyloidosis; biopsy of affected tissue is typically used for confirmation of diagnosis. PMID: 6802926 ] [Lab Tests Online:free-light/tab/test] Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Immunoglobulin light chains.kappa
- Part Display Name
- Kappa light chains
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Kappa LC
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 免疫球蛋白轻链.Kappa 型 Synonyms: Kappa LC; |
| es-ES | Spanish (Spain) | Cadenas ligeras de las inmunoglobulinas.kappa |
| it-IT | Italian (Italy) | Immunoglobuline, catene leggere.kappa Synonyms: Catene leggere kappa delle immunoglobuline |
| et-EE | Estonian (Estonia) | Immuunoglobuliini kerged ahelad.kapa Synonyms: Immuunglobuliinide kerged kapaahelad |
| tr-TR | Turkish (Turkey) | İmmünglobulin hafif zincirler.kappa |
| ru-RU | Russian (Russian Federation) | Иммуноглобулин легкие цепи.каппа |
| fr-BE | French (Belgium) | Chaînes légères immunoglobulines.kappa Synonyms: LC. Kappa |
| fr-CA | French (Canada) | Chaînes légères d'immunoglobulines.kappa |
| nl-NL | Dutch (Netherlands) | immunoglobuline lichte ketens.kappa |
| pl-PL | Polish (Poland) | Łańcuchy lekkie immunoglobuliny.kappa Synonyms: Łańcuchy lekkie kappa immunoglobuliny |
| el-GR | Greek (Greece) | Ελαφριές αλυσίδες ανοσοσφαιρίνης.κάπα Synonyms: Ελαφριές αλυσίδες ανοσοσφαιρίνης.κάπα |
LOINC Copyright
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