Version 2.78

Description

All immunoglobulins contain two polypeptide chains: a long (heavy) and a short (light) chain. The two chains interact via disulfide bonds. There are two types of light chains, named kappa and lambda. Serum free light chain (SFLC) testing, a kappa/lambda ratio and a protein electrophoresis test are done to help detect, diagnose and monitor plasma cell disorders (dyscrasias) including multiple myeloma and primary amyloidosis. Normal readings are seen when there is a kappa/lambda ratio of approximately 0.26 to 1.65 and free light chains are present in the blood at low levels. Increased kappa free light chains and an increased kappa/lambda ratio are present with plasma cell disorders that produce excess monoclonal kappa light chains. The tests can also be used to monitor response to treatment. An increase in serum free light chains along with an abnormal kappa/lambda ratio may indicate primary amyloidosis; biopsy of affected tissue is typically used for confirmation of diagnosis. PMID: 6802926 ] [Lab Tests Online:free-light/tab/test] Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Kappa light chains
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Kappa LC

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP15030-7

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 免疫球蛋白轻链.Kappa 型
Synonyms: Kappa LC;Kappa 型免疫球蛋白轻链;Kappa 型轻链;Kappa 轻链;κ型免疫球蛋白轻链;κ型轻链;κ轻链;免疫球蛋白轻链.Kappa;免疫球蛋白轻链.κ型;轻链.Kappa;轻链.Kappa 型;轻链.κ;轻链.κ型
fr-CA French (Canada) Chaînes légères d'immunoglobulines.kappa
et-EE Estonian (Estonia) Immuunoglobuliini kerged ahelad.kapa
Synonyms: Immuunglobuliinide kerged kapaahelad
es-ES Spanish (Spain) Cadenas ligeras de las inmunoglobulinas.kappa
it-IT Italian (Italy) Immunoglobuline, catene leggere.kappa
Synonyms: Catene leggere kappa delle immunoglobuline
tr-TR Turkish (Turkey) İmmünglobulin hafif zincirler.kappa
ru-RU Russian (Russian Federation) Иммуноглобулин легкие цепи.каппа
nl-NL Dutch (Netherlands) immunoglobuline lichte ketens.kappa
fr-BE French (Belgium) Chaînes légères immunoglobulines.kappa
Synonyms: LC. Kappa
pl-PL Polish (Poland) Łańcuchy lekkie immunoglobuliny.kappa
Synonyms: Łańcuchy lekkie kappa immunoglobuliny