Version 2.78

Description

The myeloblast is a unipotent stem cell, which will differentiate into one of the effectors of the Granulocyte series.

These cells descend from the primitive reticulum cells, which are found in the stroma of the marrow. There is also an intermediate phase between the myeloblast and these primitive reticulum cell, namely the hemocytoblast. At this time several developing blood cell lines are available, like erythropoiesis and thrombopoiesis. The granulopoiesis is regulated by humoral agents, like Colony Stimulating Factor and Interleukin 3.

Most common problem with malfunctioning myeloblasts is the acute myeloblastic leukemia. The main clinical features are caused by failure of the hemopoiesis with anemia, hemorrhage and infection as result. There is a progressive accumulation of leukemic cells, because some blast progenitor cells renew themselves and will have a limited differentiated division. Key mediators are the cell-density and Colony Stimulating Factor(CSF). A few acute myeloblastic leukemia can be initiated by earlier hematologic disorder, like pancytopenia, hypoplasia of the bone marrow. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Myeloblasts (Wikipedia)

Basic Part Properties

Part Display Name
Myeloblasts
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Myeloblasts

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP15076-0

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 原始粒细胞
Synonyms: 原粒细胞;成血球细胞;成髓细胞
fr-CA French (Canada) Myéloblastes
et-EE Estonian (Estonia) Müeloblastid
es-ES Spanish (Spain) Mieloblastos
it-IT Italian (Italy) Mieloblasti
tr-TR Turkish (Turkey) Miyeloblastlar
ru-RU Russian (Russian Federation) Миелобласты
nl-NL Dutch (Netherlands) myeloblasten
fr-BE French (Belgium) Myéloblastes