LP15323-6
Adenosine deaminase
Active
Descriptions
An enzyme that catalyzes the hydrolysis of adenosine to inosine with the elimination of ammonia. Since there are wide tissue and species variations in the enzyme, it has been used as a tool in the study of human and animal genetics and in medical diagnosis. EC 3.5.4.4. Source: National Library of Medicine, MeSH 2006
Adenosine deaminase (ADA) is a purine salvage pathway enzyme, which catalyzes the irreversible deamination of adenosine into inosine and ammonia. Elevated adenosine deaminase activities are found in tuberculous pleural and pericardial effusions. In addition, increased ADA levels in cerebrospinal fluid (CSF) have been observed in tuberculous meningitis. These ADA increases are caused by the cellular immune response in the fluid compartment, especially in the activation of T lymphocytes. Thus, many disorders can cause elevations. Deficency of adenosine deaminase is the most frequent known cause of SCID (Severe combined immunodeficency disease) it is observed in 25% of cases. Source: Regenstrief Institute
Basic Part Properties
- Part Name
- Adenosine deaminase
- Part Display Name
- Adenosine deaminase
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Adenosine deaminase
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 腺苷脱氨酶 Synonyms: ADA; |
| es-ES | Spanish (Spain) | Adenosina deaminasa |
| it-IT | Italian (Italy) | Adenosina deaminasi |
| et-EE | Estonian (Estonia) | Adenosiini deaminaas |
| tr-TR | Turkish (Turkey) | Adenozin deaminaz |
| ru-RU | Russian (Russian Federation) | Аденозин деаминаза Synonyms: Аденозиндезаминаза |
| fr-BE | French (Belgium) | Adénosine déaminase Synonyms: ADA |
| fr-CA | French (Canada) | Adénosine déaminase |
| nl-NL | Dutch (Netherlands) | adenosinedeaminase |
| el-GR | Greek (Greece) | Αδενοσινοδεαμινάση Synonyms: Αδενοσινοδεαμινάση |
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