LP15346-7
Alkaline phosphatase
Active
Descriptions
An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1. Source: National Library of Medicine, MeSH 2006
Alkaline phosphatase (ALP, ALKP) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. ALP is present in all tissues throughout the entire body, but is particularly concentrated in liver, bile duct, kidney, bone, and the placenta. Humans and most other mammals contain the following ALP isozymes: ALPI (intestinal), ALPL (tissue non-specific, liver/bone/kidney), and ALPP (placental, aka Regan isozyme).
The normal range of alkaline phosphatase is 20 to 140 IU/L. High ALP levels are present in children and pregnant women, if bile ducts are blocked, and in the presence of osteoblast activity, such as with Paget's disease of the bone. Lowered levels of ALP are less common than elevated levels and occurs in various conditions, including aplastic and pernicious anemias, chronic myelogenous leukemia, Wilson's disease, children with severe enteritis, and postmenopausal women on estrogen therapy for osteoporosis.
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Source: Wikipedia, Alkaline phosphatase (Wikipedia)
Basic Part Properties
- Part Display Name
- Alkaline phosphatase
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- ALP
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 碱性磷酸酶 Synonyms: ALKP; |
| fr-CA | French (Canada) | Phosphatase alcaline |
| et-EE | Estonian (Estonia) | Aluseline fosfataas |
| es-ES | Spanish (Spain) | Fosfatasa alcalina total |
| it-IT | Italian (Italy) | Fosfatasi alcalina |
| el-GR | Greek (Greece) | Αλκαλική φωσφατάση Synonyms: ALP |
| tr-TR | Turkish (Turkey) | Alkalen fosfataz |
| ru-RU | Russian (Russian Federation) | Щелочная фосфатаза |
| nl-NL | Dutch (Netherlands) | alkalische fosfatase |
| fr-BE | French (Belgium) | Phosphatase alcaline Synonyms: ALP |
| pl-PL | Polish (Poland) | Fosfataza zasadowa |
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