LP17751-6
Cells.CD20
Active
Description
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein on the surface of all B-cells starting at the pro-B phase (CD45R+, CD117+) and increases in concentration until maturity. In humans CD20 is encoded by the MS4A1 gene. This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule that plays a role in the development and differentiation of B-cells into plasma cells. CD20 is the target of the monoclonal antibodies (mAb) rituximab, Ibritumomab tiuxetan, and tositumomab, that are active agents in the treatment of all B cell lymphomas and leukemias. The anti-CD20 mAB Ofatumumab (Genmab) was approved by FDA in Oct 2009 for Chronic lymphocytic leukemia. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, CD20
Basic Part Properties
- Part Display Name
- CD20 cells
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- CD20 Cells
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP17751-6
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 细胞.CD20 Synonyms: CD20细胞 |
| fr-CA | French (Canada) | Cellules.CD20 |
| et-EE | Estonian (Estonia) | Rakud.CD20 |
| es-ES | Spanish (Spain) | Células CD20+ |
| it-IT | Italian (Italy) | Cellule.CD20 Synonyms: Cellule CD20 |
| tr-TR | Turkish (Turkey) | Hücreler.CD20 |
| ru-RU | Russian (Russian Federation) | Клетки.CD20 |
| nl-NL | Dutch (Netherlands) | cellen.CD20 |
| fr-BE | French (Belgium) | Cellules.CD20 |
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