Version 2.78

Description

Norclozapine (desmethyl-clozapine),a major metabolite of clozapine, is pharmacologically active. The cytochrome P450 isoenzyme 1A2 is primarily responsible for clozapine metabolism, but 2C, 2D6, 2E1 and 3A3/4 appear to play roles as well. Agents which induce (e.g. cigarette smoke) or inhibit (e.g. theophylline, ciprofloxacin, fluvoxamine) CYP1A2 may increase or decrease, respectively, the metabolism of clozapine. For example, the induction of metabolism caused by smoking means that smokers require up to double the dose of clozapine compared with non-smokers to achieve an equivalent plasma concentration. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Norclozapine

Basic Part Properties

Part Display Name
Norclozapine
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Norclozapine

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP18081-7
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP18081-7

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 去甲基氯氮平
Synonyms: 脱甲基氯氮平;去甲基氯扎平;去甲氯扎平;去甲氯氮平;氯扎平代谢产物;氯氮平代谢产物
fr-CA French (Canada) Norclozapine
et-EE Estonian (Estonia) Norklosapiin
es-ES Spanish (Spain) Norclozapina
it-IT Italian (Italy) Norclozapina
tr-TR Turkish (Turkey) Norklozapin
ru-RU Russian (Russian Federation) Норклозапин
nl-NL Dutch (Netherlands) norclozapine
fr-BE French (Belgium) Norclozapine