Version 2.78

Description

Human Leukocyte Antigen B*27 (subtypes B*2701-2724) is a class I surface antigen encoded by the B locus in the major histocompatibility complex (MHC) on chromosome 6. It presents microbial antigens to T-cells and is strongly associated with certain immunity diseases (SpA spondyloarthropathies). In the general population, about 8% Caucasian, 4% African, 2-9% Chinese, and 0.1-0.5% Japanese have the HLA-B27 antigen. In Northern Scandinavia (Lapland), 24% of people are HLA-B27 positive while 1.8% have ankylosing spondylitis (AS). Mystery:The relationship between HLA-B27 and many diseases has not yet been fully elucidated. Though it is associated with a wide range of pathology, it does not appear to be the sole mediator in development of disease. For example, while nearly all people with ankylosing spondylitis (AS) are HLA-B27 positive, only a fraction of people with HLA-B27 ever develop AS. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, HLA-B (Wikipedia)

Basic Part Properties

Part Display Name
HLA-B
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
HLA-B

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP18320-9

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) HLA-B
fr-CA French (Canada) HLA-B
et-EE Estonian (Estonia) HLA-B
es-ES Spanish (Spain) HLA-B
it-IT Italian (Italy) HLA-B
tr-TR Turkish (Turkey) HLA-B
ru-RU Russian (Russian Federation) HLA-B
nl-NL Dutch (Netherlands) HLA-B
fr-BE French (Belgium) HLA-B