LP18426-4
5-Hydroxyhexanoate
Active
Description
5-Hydroxyhexanoic acid (also known as 5-Hydroxycaproic acid) is a normal dicarboxylic acid degradation product of fatty acids; however, it has been found in patients with non-ketotic dicarboxylic aciduria and one patient on a diet containing excessive amounts of medium-chain triglycerides. Increased amounts of dicarboxylic acids are excreted in human urine under conditions of medium-chain triglyceride (MCT) feeding, abnormal fatty acid oxidation (FAO) and fasting. Criteria to distinguish dicarboxylic aciduria originating from MCT feeding and other conditions are needed in urinary organic acid profiling for detecting inborn errors of metabolism. Medium-chain triglycerides (MCTs) are absorbed and metabolized differently from long-chain triglycerides (LCTs). MCTs may be useful as a dietary substitute in a variety of clinical disorders. Urinary excretion of 5-hydroxyhexanoic acid, the (omega-1) hydroxylation product, was increased during MCT feeding as compared with LCT feeding in patients with non-insulin-dependent diabetes mellitus. PMID: 6897376, PMID: 2239769, PMID: 8596483 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, 5-Hydroxyhexanoic acid
Basic Part Properties
- Part Display Name
- 5-Hydroxyhexanoate
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- 5OH-Hexanoate
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Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 5-羟基己酸 Synonyms: 5OH-己酸 |
fr-CA | French (Canada) | 5-hydroxyhéxanoate |
et-EE | Estonian (Estonia) | 5-hüdroksüheksanoaat |
es-ES | Spanish (Spain) | 5-Hidroxihexanoato |
it-IT | Italian (Italy) | 5-Idrossiesanoato |
tr-TR | Turkish (Turkey) | 5-Hidroksihekzanoat |
ru-RU | Russian (Russian Federation) | 5-Гидроксигексаноат |
nl-NL | Dutch (Netherlands) | 5-hydroxyhexanoaat |
fr-BE | French (Belgium) | 5-hydroxyhéxanoate |
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