Version 2.77

Description

HLA-C, along with HLA-B and HLA-A, is a class I major histocompatibility complex (MHC) receptor, which are keys to antigen presentation in the immune system. It is coded by the HLA-C gene located on human chromosome 6. The class I molecules are heterodimers composed of one alpha subunit (the product of the class I gene) and a beta subunit, beta2 microglobulin. The high variability of this class of molecules is likely key to protecting the humans from pathogens, as it is more likely that a subset of the population will be highly immune to any given pathogen, and this diversity is reflected in the hundreds to thousands of possible alleles. However, the variability in HLA is also the reason for transplant rejection, and the detection of HLA antibodies in the transplant recipient has become a critical pre-transplant assessment. [https://www.genecards.org/cgi-bin/carddisp.pl?gene=HLA-C] Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
HLA-C IgG
Part Type
Component (Describes the core component or analyte measured)
Created On
2015-06-18

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP193954-7

Language Variants Get Info

Tag Language Translation
pl-PL Polish (Poland) HLA-C Ab.IgG
Synonyms: PrzeciwciaƂa IgG do HLA-C