Version 2.78

Description

The a-wave is an electroretinographic measurement of the initial corneal-negative deflection, derived from the cones and rods of the outer photoreceptor layers. This wave reflects the hyperpolarization of the photoreceptors due to closure of sodium ion channels in the outer-segment membrane. Absorption of light triggers the rhodopsin to activate transducin, a G-protein, which leads to the activation of cyclic guanosine monophosphate phosphodiesterase (cGMP PDE) and eventually to a reduction in the level of cGMP within the photoreceptor. Reduction in cGMP leads to closure of the sodium ion channels, which results in a decrease of inwardly directed sodium ions, or hyperpolarization of the cell. The a-wave amplitude is measured from baseline to the trough of the a-wave. Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
a-wave amplitude
Part Type
Component (Describes the core component or analyte measured)
Created On
2015-10-07
Construct for LOINC Short Name
a-wave amp

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP200585-0

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) a-波振幅
Synonyms: a-波振幅(波幅、波幅度、幅度)
it-IT Italian (Italy) onda A ampiezza
Synonyms: ampiezza dell''Onda A