Version 2.78

Description

Cytochrome P450-2C19 (CYP2C19; [HGNC Gene ID: 2621]), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism 10-15% of drugs in current clinical use. Genetic variations in CYP2C19 can affect the response (i.e., efficacy or toxicity) to drugs metabolized by CYP2C19 and selection of alternative dosing or agents may be necessary in individuals with specific CYP2C19 genetic variations. PMID: 23486447 PMID: 23698643 PMID: 25974703 See https://www.pharmgkb.org/gene/PA124 for more information and dosing guidelines for drugs impacted by CYP2C19 genetic variation. Source: Clinical Pharmacogenetics Implementation Consortium

Basic Part Properties

Part Display Name
CYP2C19 gene product metabolic activity interpretation
Part Type
Component (Describes the core component or analyte measured)
Created On
2015-11-09
Construct for LOINC Short Name
CYP2C19 gene prod met act imp

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP202918-1

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) CYP2C19 基因产物新陈代谢活性解释
Synonyms: CYP2C19 基因产物新陈代谢（代谢）活性解释（说明、阐释、诠释、解释说明）
es-ES Spanish (Spain) Gen CYP2C19 interpretation de la actividad en el metabolismo de fármacos
it-IT Italian (Italy) Interpretazione dell'attività metabolica del gene CYP2C19
tr-TR Turkish (Turkey) CYP2C19 geni ürünü metabolik aktivite yorumu
nl-NL Dutch (Netherlands) CYP2C19-gen product metabole activiteit interpretatie
Synonyms: CYP2C19 gen product metabole activiteit interpretatie