LP222259-6
Recoverin
Active
Description
Recoverin is a calcium-binding photoreceptor protein that has been identified as the target of autoantibodies that results in cancer-associated retinopathy (CAR). CAR is a paraneoplastic syndrome where autoantibodies against an unknown neoplasm cross-react with retinal photoreceptor antigens and damage them leading to vision loss. PMID: 7568096 Only 65% of patients with CAR have detectable antiretinal antibodies and antibodies specific to recoverin are found in approximately 10% of those patients. Most tumors associated with CAR include small-cell lung cancer and gynecological malignancies. Neoplasms that are less often associated with CAR include bladder, prostate, pancreatic, small bowel, thymus, thyroid and colon. PMID: 26862417 Recoverin antibodies lead to cancer-associated retinopathy and have been shown to induce apoptotic death to photoreceptor cells. PMID: 12417436 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Recoverin
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2016-09-12
- Construct for LOINC Short Name
- Recoverin
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP222259-6
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 恢复蛋白 Synonyms: 恢复素; |
| es-ES | Spanish (Spain) | Recoverina |
| it-IT | Italian (Italy) | Recoverin |
| nl-NL | Dutch (Netherlands) | recoverine |
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright