Version 2.78

Description

The existence of OXA-48 like class D beta-lactamases has been increasing in enterobacter species organisms. The "OXA-like" groups of genes are molecularly similar to and thought to evolve from the original gene for which the group is named. For example, as of 2014 the blaOXA-23-like group included 19 genes, including including blaOXA-23, -27, -49, and -73. PMID: 24696435. The OXA-48 like class D beta-lactamase enzymes are highly resistant to penicillins and beta lactamase inhibitors and show a low resistance to carbapenems. These varied OXA-48-like beta-lactamases have been identified worldwide, including OXA-48-like producing Klebsiella pneumoniae with resistance to multiple drugs that emerged in Jordanian hospitals. Reports have shown that organisms producing OXA-48 like enzymes are either not resistant to broad-spectrum cephalosporins or show a decreased susceptibility to carbapenemase drugs. Identifying them can be a challenge. Screening and detection is required to prevent and control dissemination. PMID: 22499996 PMID: 26993738 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Bacterial carbapenem resistance bla OXA-48-like gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2017-02-20
Construct for LOINC Short Name
blaOXA-48-like

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP248274-5

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) gen bacteriano similar blaOXA-48 resistente a carbapenem
zh-CN Chinese (China) 细菌碳青霉烯类耐药 blaOXA-48-样基因
Synonyms: 细菌细菌碳青霉烯类（碳青霉烯类抗生素、碳青霉烯）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） blaOXA-48-样基因
it-IT Italian (Italy) Resistenza batterica ai carbapenemici, gene blaOXA-48-like
Synonyms: Gene blaOXA-48-like di resistenza batterica ai carbapenemi
nl-NL Dutch (Netherlands) bacteriële carbapenemresistentie blaOXA-48-achtig gen
Synonyms: blaOXA-134-like