Version 2.77

Description

Plasma cells are fully differentiated B lymphocytes that produce and secrete a specific antibody.[https://www.cancer.gov/types/myeloma/patient/myeloma-treatment-pdq] Plasma cells typically produce a mixture of kappa and lambda light chains, but monotypic (or monoclonal) plasma cells produce either elevated kappa or lambda light chains.[http://hematologyoutlines.com/atlas_topics/76.html] Monotypic plasma cells are characteristic of disorders such as leukemia and multiple myeloma. The use of multi-parameter flow cytometry makes it possible to analyze large numbers of cells that distinguish intracellular antigens. Not only does such technology improve the diagnosis of monotypic populations, but it also is important for monitoring treatment and demonstrating smoldering disease. PMID: 21112041 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Plasma cells monotypic population
Part Type
Component (Describes the core component or analyte measured)
Created On
2017-04-07
Construct for LOINC Short Name
Monotypic plasma cells

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP249103-5

Language Variants Get Info

Tag Language Translation
it-IT Italian (Italy) Plasmacellule.popolazione monotipica
Synonyms: Popolazione monotipica plasmacellule
es-ES Spanish (Spain) Células plasmáticas, población monoclonal
zh-CN Chinese (China) 浆细胞.单型群
Synonyms: 浆细胞.单一型群;浆细胞.单型总体(群体、母体、样本总体)
nl-NL Dutch (Netherlands) plasmacellen.monotypische populatie
pl-PL Polish (Poland) Plazmocyty, populacja monoklonalna