LP260859-6
Varicella zoster virus clade
Active
Description
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/
Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Varicella zoster virus clade
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2017-06-02
- Construct for LOINC Short Name
- VZV clade
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Clados del virus de Varicela Zoster |
| zh-CN | Chinese (China) | 水痘带状疱疹病毒进化枝 Synonyms: 水痘带状疱疹病毒（HHV-3、 |
| it-IT | Italian (Italy) | Varicella zoster virus clade |
| nl-NL | Dutch (Netherlands) | varicella-zostervirus clade Synonyms: Varicella zoster virus clade |
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