LP29023-6
Coagulation factor VIII inhibitor
Active
Description
Factor VIII replacement is the foundational treatment for hemophilia A, and the developement of alloantibodies (known as inhibitors) against the replacement factor is the most important complication causing morbidity in hemophilia patients. Antibodies against factor VIII can be inhibitory or noninhibitory, with inhibitors generally being polycloncal IgG directed against the A2, A3 and C2 domains of the factor VIII molecule. The resulting steric hindrance can block functional epitopes including FIX, phospholipid, or von Willebrand binding sites PMID: 23610614. Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Coagulation factor VIII inhibitor
- Part Display Name
- Coagulation factor VIII inhibitor
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2002-06-18
- Construct for LOINC Short Name
- Fact VIII Inhib
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 凝血因子 VIII 抑制剂 Synonyms: 凝血因子 VIII（凝血因子Ⅷ、 |
| es-ES | Spanish (Spain) | Factor de coagulación VIII inhibido |
| it-IT | Italian (Italy) | Fattore di coagulazione VIII, inibitore Synonyms: Inibitore del fattore di coagulazione VIII |
| et-EE | Estonian (Estonia) | VIII faktori inhibiitor |
| tr-TR | Turkish (Turkey) | Koagülasyon faktörü VIII inhibitörü |
| ru-RU | Russian (Russian Federation) | Коагуляции фактор VIII ингибитор |
| fr-BE | French (Belgium) | Inhibiteur du facteur VIII |
| fr-CA | French (Canada) | Inhibiteur du facteur VIII |
| nl-NL | Dutch (Netherlands) | stollingsfactor VIII remmer |
| pl-PL | Polish (Poland) | Inhibitor Czynnika krzepnięcia VIII |
| el-GR | Greek (Greece) | Αναστολέας παράγοντα πήξης VIII Synonyms: Αναστολέας παράγοντα πήξης VIII |
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