Version 2.78

Description

These are two chemically unrelated compounds from the streptogramin family that act synergistically. Used to treat vancomycin resistant enterococcus (VRE) due to E. faecium (NOT E. faecalis), and methicillin resistant staph aureus (MRSA). The Quinupristin / Dalfopristin combination inhibits protein synthesis by interfering with different targets on the rRNA 23S in the 50S ribosomal subunit. The synergy appears to be based on ribosomal conformational changes triggered by the binding of the streptogramin A (Dalfopristin), which can cause irreversible attachment of the streptogramin B (Quinupristin) to the ribosome. Source: Regenstrief Institute

Basic Part Properties

Part Display Name
Quinupristin+Dalfopristin
Part Type
Component (Describes the core component or analyte measured)
Created On
2002-06-18
Construct for LOINC Short Name
Quinupristin+Dalfoprist

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP29104-4

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 奎奴普丁+达福普汀
fr-CA French (Canada) Quinupristine+Dalfopristine
et-EE Estonian (Estonia) Kinupristiin + dalfopristiin
es-ES Spanish (Spain) Quinupristina+Dalfopristina
it-IT Italian (Italy) Quinupristina+Dalfopristina
tr-TR Turkish (Turkey) Kuinupristin+Dalfopristin
ru-RU Russian (Russian Federation) Квинупристин+Дальфопристин
nl-NL Dutch (Netherlands) quinupristine + dalfopristine
fr-BE French (Belgium) Quinupristine+Dalfopristine