Version 2.78

Description

Doravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed to treat drug-resistant HIV. Compared to second-generation NNRTI drugs that target drug-resistant HIV-1 mutants that are currently on the market (etravirine and rilpivirine), it has better antiviral activity in treatment-naive patients as well as a better safety profile. Despite its efficacy in treating resistant strains of HIV-1, it is not as effective in treating the wild type strain of HIV. PMID: 30606670 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Doravirine
Part Type
Component (Describes the core component or analyte measured)
Created On
2019-03-18
Construct for LOINC Short Name
Doravirine

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP310284-7
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 多拉韦林
Synonyms: MK-1439;MK1439;Pifeltro;3-氯-5-((1-((4-甲基-5-氧代-4,5-二氢-1H-1,2,4-噻唑-3-基)甲基)-2-氧代-4-(三氟甲基)-1,2-二氢吡啶-3-基)氧基)苯甲腈;3-chloro-5-[1-[(4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)pyridin-3-yl]oxybenzonitrile;新型的非核苷的HIV-1逆转录酶抑制剂
it-IT Italian (Italy) Doravirina
es-ES Spanish (Spain) Doravirina
pl-PL Polish (Poland) Dorawiryna
Synonyms: Dorawiryna