Version 2.77

Description

The ITGA2B gene (integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)) [HGNC Gene ID:6138] is located on chromosome 17q21.32. ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008] [NCBI Gene ID:3674] Source: National Center for Biotechnology Information (NCBI) Gene

Basic Part Properties

Part Display Name
Platelet CD41
Part Type
Component (Describes the core component or analyte measured)
Created On
2019-06-28
Construct for LOINC Short Name
Plt CD41

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP410814-0

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 血小板 CD41
it-IT Italian (Italy) Piastrine CD41
es-ES Spanish (Spain) CD41 plaquetario
pl-PL Polish (Poland) Płytkowy antygen CD41