LP410916-3
Neutrophils.CD64
Active
Description
CD64, also known as Fc gamma receptor I, is a transmembrane glycoprotein that is part of the large immunoglobulin (Ig) superfamily. CD64 is encoded by 3 genes (FCγRI A-C), one for the transmembrane region and the other 2 for the Ig-like domains. CD64 is consitutively expressed on monocytes and macrophages (but inducible on neutrophils), and it has a pivotal role in antibody-dependent cytotoxicity and clearance of immune complexes. The presence of this molecule on neutrophils can aid in the diagnosis of infection and sepsis, and immuotherapeutic agents targeting CD64 have emerged as candidates for treatment of chronic inflammatory diseases such as atopic dermatitis, rheumatoid arthritis, and autoimmune disorders PMID: 28895912. Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Neutrophils.CD64
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2019-07-15
- Construct for LOINC Short Name
- Neut.CD64
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP410916-3
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 嗜中性粒细胞.CD64 Synonyms: 嗜中性粒细胞（中性、 |
| it-IT | Italian (Italy) | Neutrofili.CD64 Synonyms: Neutrofili CD64 |
| nl-NL | Dutch (Netherlands) | neutrofielen.CD64 |
| es-ES | Spanish (Spain) | Neutrófilos.CD64 |
LOINC Copyright
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