Version 2.77

Descriptions

Tauroursodeoxycholic acid (TUDCA) is a secondary bile acid. It is produced in the liver when ursodeoxycholic acid is conjugated to taurine. TUDCA has cytoprotective properties and is used to treat chronic liver diseases associated with cholestasis. It also may have neuroprotective effects and is a potential therapy for neurodegenerative conditions such as amyotrophic lateral sclerosis. PMID: 25664595 Source: Regenstrief LOINC

Bile acids (BAs) are conjugated to either taurine or glycine. Various disorders are associated with different BA profiles. Alcoholic cirrhosis has been associated with extremely high levels of the taurine-conjugated BAs taurocholate, taurochenodeoxycholate, and tauroursodeoxycholate, moderately elevated levels of glycine-conjugated BAs, including glycocholate, glycochenodeoxycholate, and glycoursodeoxycholate, and mild elevation of nonconjugated BAs (cholate, chenodeoxycholate). [PMID: 30976744] Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Tauroursodeoxycholate
Part Type
Component (Describes the core component or analyte measured)
Created On
2019-07-25
Construct for LOINC Short Name
TUDCA

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 牛磺熊去氧胆酸
Synonyms: 牛磺熊脱氧胆酸;TUDCA;3α，7β二羟基胆烷酰-N-牛磺酸;CAS 14605-22-2
nl-NL Dutch (Netherlands) tauro-ursodeoxycholaat
it-IT Italian (Italy) Tauroursodesossicolato
es-ES Spanish (Spain) Tauroursodeoxicolato