Version 2.78

Description

The major histocompatibility complex (MHC) class I (A, B, and C) and II (DP, DM, DOA, DOB, DQ, and DR) in the human leukocyte antigen (HLA) system contains a large number of genes involved in immune system function in humans. The proteins encoded by some genes form antigens. HLA class I and II antigens are widely distributed on all nucleated cells and carried by platelets.

Antibodies specific to HLA class I and II antigens can be acquired through alloimmunization due to pregnancy, transfusion of blood products, or previous transplants. Alloimmunization can lead to production of antibodies in approximately one third of individuals. The presence of antibodies, specifically IgG, can affect the survival of transplant allografts or transfused platelets in sensitized individuals. Various testing methods are used to detect antibodies to HLA antigens. Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
HLA-A and B and C (class I) IgG high risk
Part Type
Component (Describes the core component or analyte measured)
Created On
2020-02-06
Construct for LOINC Short Name
HLA class I Ab.IgG high risk

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP417652-7

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) HLA-A 与 B 与 C (I 类) 抗体.IgG 高度风险
Synonyms: HLA-A 与 B 与 C (I 类) 抗体（Ab）.IgG 高度风险（高危、高风险、高等风险）;人类白细胞抗原;人白细胞抗原;human leukocyte antigen;HLA
nl-NL Dutch (Netherlands) HLA A & B & C (klasse I) As.IgG hoog risico
it-IT Italian (Italy) HLA-A & B & C (classe I) Ab.IgG, rischio elevato
Synonyms: Rischio elevato di HLA-A & B & C (classe I) Ab.IgG
es-ES Spanish (Spain) HLA-A , B , C (clase I) alto riesgo por Ac IgG
pl-PL Polish (Poland) HLA-A & B & C (klasa I) Ab.IgG wysokiego ryzyka
Synonyms: Przeciwciała IgG do HLA-A, B i C (klasa I) wysokiego ryzyka