LP62171-1

Quinolinate

Active

Description

Quinolinic acid is a dicarboxylic acid. It may be prepared by the oxidation of quinoline, either electrochemically, or with acidic hydrogen peroxide.

Quinolinic acid is a downstream kynurenine pathway metabolite of tryptophan. Quinolinic acid has a potent neurotoxic effect and involved in neurodegenerative processes in the brain, such as in AIDS dementia complex, Alzheimer's disease, Huntington's disease, amyotrophic lateral sclerosis, multiple sclerosis and Parkinson's disease. Within the brain, quinolinic acid is only produced by activated microglia and macrophages. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Basic Part Properties

Part Name

Quinolinate

Part Display Name

Quinolinate

Part Type

Component (Describes the core component or analyte measured)

Created On

2007-01-10

Construct for LOINC Short Name

Quinolinate

Related Codes

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