Version 2.78

Description

Non-susceptibility to carbapenems in gram-negative bacilli by means of the enzyme KPC (Klebsiella pneumoniae carbapenemase) is becoming more common. The gene beta-lactamase KPC (bla(KPC)) encodes KPC enzyme production, which in turn hydrolyzes and inactivates carbapenem antibiotics. KPC enzymes are a class A beta lactamases with several variants (KPC-2, KPC-3, etc) known. Various methods are used to detect specific portions of genes encoding KPC production. Carbapenemases can also be detected by other methods, including the modified Hodge test to detect carbapenemase production in isolates and minimum inhibitory concentration (MIC) to determine level of resistance. Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Bacterial carbapenem resistance blaKPC gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2007-07-23
Construct for LOINC Short Name
blaKPC

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP64707-0

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 细菌碳青霉烯类耐药 blaKPC 基因
Synonyms: 细菌碳青霉烯类（碳青霉烯类抗生素、碳青霉烯）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） blaKPC 基因;细菌碳青霉烯酶（碳青黴烯酶、碳青霉烯水解酶）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型）blaKPC 基因
fr-CA French (Canada) Gène bactérien de résistance à la carbapéném blaKPC
es-ES Spanish (Spain) Gen bla(KPC)
it-IT Italian (Italy) Resistenza batterica ai carbapenemici, gene blaKPC
Synonyms: Gene blaKPC di resistenza batterica ai carbapenemici
tr-TR Turkish (Turkey) Bakteriyel karbapenemaz direnç (bla(KPC)) geni
ru-RU Russian (Russian Federation) Бактериальная карбапенемаза резистентность (bla(KPC)) ген
nl-NL Dutch (Netherlands) bacteriële carbapenemresistentie blaKPC-gen
fr-BE French (Belgium) Résistance bacterienne carbapénémase (bla(KPC)) gène