14851-0
Norclozapine [Moles/volume] in Serum or Plasma
Active
Part Description
LP18081-7 Norclozapine
Norclozapine (desmethyl-clozapine),a major metabolite of clozapine, is pharmacologically active. The cytochrome P450 isoenzyme 1A2 is primarily responsible for clozapine metabolism, but 2C, 2D6, 2E1 and 3A3/4 appear to play roles as well. Agents which induce (e.g. cigarette smoke) or inhibit (e.g. theophylline, ciprofloxacin, fluvoxamine) CYP1A2 may increase or decrease, respectively, the metabolism of clozapine. For example, the induction of metabolism caused by smoking means that smokers require up to double the dose of clozapine compared with non-smokers to achieve an equivalent plasma concentration.
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Source: Wikipedia, Norclozapine
Fully-Specified Name
- Component
- Norclozapine
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Norclozapine [Moles/volume] in Serum or Plasma
- Short Name
- Norclozapine SerPl-sCnc
- Display Name
- Norclozapine [Moles/Vol]
- Consumer Name Alpha Get Info
- Norclozapine, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0k
- Last Updated
- Version 2.34
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG47389-8 | Norclozapine| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Norclozapin: Synonyms: Desmethylclozapin |
es-AR | Spanish (Argentina) | norclozapina: |
es-ES | Spanish (Spain) | Norclozapina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Norclozapina: |
et-EE | Estonian (Estonia) | Norklosapiin: Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Norclozapine: |
fr-FR | French (France) | Norclozapine: |
fr-BE | French (Belgium) | Norclozapine: |
it-IT | Italian (Italy) | Norclozapina: Synonyms: Concentrazione di Sostanza Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | Norclozapine: |
nl-NL | Dutch (Netherlands) | norclozapine: |
pt-BR | Portuguese (Brazil) | Norclozapina: Synonyms: Clozapine metAcolite; |
ru-RU | Russian (Russian Federation) | Норклозапин: Synonyms: Количественный Молярность; |
tr-TR | Turkish (Turkey) | Norklozapin: |
zh-CN | Chinese (China) | 去甲基氯氮平: Synonyms: 克分子浓度; |
Example Units
Unit | Source |
---|---|
nmol/L | Example UCUM Units |
nmol/L | eCHN |
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