26492-9
Mononuclear cells/Leukocytes in Cerebral spinal fluid
Active
Part Descriptions
LP157588-7 Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010)
Source: Regenstrief LOINC
LP17839-9 Mononuclear cells
A Peripheral Blood Mononuclear Cell (PBMC) is a blood cell having a round nucleus, such as a lymphocyte or a monocyte. These blood cells are a critical component in the immune system to fight infection and adapt to intruders. The lymphocyte population consists of T cells (CD4 and CD8 positive ~75%), B cells and NK cells (~25% combined).
These cells are often extracted from whole blood using ficoll, a hydrophilic polysaccharide that separates layers of blood, with monocytes and lymphocytes forming a buffy coat under a layer of plasma. This buffy coat contains the PBMCs. Additionally, PBMC can be extracted from whole blood using a hypotonic lysis which will preferentially lyse red blood cells. This method results in neutrophils and other polymorphonuclear (PMN) cells which are important in innate immune defense to be obtained.
PBMCs are widely used in research and clinical uses every day. HIV research uses them because PBMCs include CD4+ cells, the cells HIV infects.
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Source: Wikipedia
, Mononuclear cell
Fully-Specified Name
- Component
- Mononuclear cells/Leukocytes
- Property
- NFr
- Time
- Pt
- System
- CSF
- Scale
- Qn
- Method
Additional Names
- Long Common Name
- Mononuclear cells/Leukocytes in Cerebral spinal fluid
- Short Name
- Mononuc Cells NFr CSF
- Display Name
- Mononuclear cells/Leukocytes (CSF)
- Consumer Name Alpha Get Info
- Mononuclear cells/White Blood Cells, Spinal fluid
Basic Attributes
- Class
- HEM/BC
- Type
- Laboratory
- First Released
- Version 2.00
- Last Updated
- Version 2.79 (NAM)
- Change Reason
- Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 10228
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54230-8 | Cell count and Diff panel with Gluc and Prot - Cerebral spinal fluid |
| 34564-5 | Cell count and Differential panel - Cerebral spinal fluid |
| 29584-0 | Differential panel - Cerebral spinal fluid |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Mononukleäre Zellen/Leukozyten: Synonyms: Zerebrospinalflüssigkeit |
| de-AT | German (Austria) | Synonyms: Mononuk.Z.rel./L |
| el-GR | Greek (Greece) | Μονοπύρηνα κύτταρα/Λευκοκύτταρα: Synonyms: NFr |
| es-AR | Spanish (Argentina) | células mononucleares/100 leucocitos: |
| es-ES | Spanish (Spain) | Mononucleares/Leucocitos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Células mononucleares / 100 leucocitos: |
| fr-CA | French (Canada) | Cellules mononucléaires/Leucocytes: |
| fr-FR | French (France) | Cellules mononucléées/100 leucocytes: |
| it-IT | Italian (Italy) | Cellule mononucleari/Leucociti: Synonyms: Ematologia (coagulazione) conta differenziale Frazione numerica Liquido cerebrospinale Punto nel tempo (episodio) |
| ko-KR | Korean (Korea, Republic Of) | 단핵세포/100 백혈구: |
| nl-NL | Dutch (Netherlands) | mononucleaire cellen/leukocyten: |
| pl-PL | Polish (Poland) | Mononuklearne komórki/leukocyty: Synonyms: Leukocyty Mononuklearne komórki Mononuklearne komórki/leukocyty |
| pt-BR | Portuguese (Brazil) | Células mononucleares/100 leucócitos: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Мононуклеарные клетки/Лейкоциты: Synonyms: Количественный Количество отношение Точка во времени; |
| tr-TR | Turkish (Turkey) | Mononükleer hücreler/Lökosit: |
| zh-CN | Chinese (China) | 单个核细胞/白细胞: Synonyms: CSF CSF; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
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LOINC Copyright
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