Version 2.80

Part Descriptions

LP157588-7   Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

LP17839-9   Mononuclear cells
A Peripheral Blood Mononuclear Cell (PBMC) is a blood cell having a round nucleus, such as a lymphocyte or a monocyte. These blood cells are a critical component in the immune system to fight infection and adapt to intruders. The lymphocyte population consists of T cells (CD4 and CD8 positive ~75%), B cells and NK cells (~25% combined).

These cells are often extracted from whole blood using ficoll, a hydrophilic polysaccharide that separates layers of blood, with monocytes and lymphocytes forming a buffy coat under a layer of plasma. This buffy coat contains the PBMCs. Additionally, PBMC can be extracted from whole blood using a hypotonic lysis which will preferentially lyse red blood cells. This method results in neutrophils and other polymorphonuclear (PMN) cells which are important in innate immune defense to be obtained.

PBMCs are widely used in research and clinical uses every day. HIV research uses them because PBMCs include CD4+ cells, the cells HIV infects. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Mononuclear cell

Fully-Specified Name

Component
Mononuclear cells/Leukocytes
Property
NFr
Time
Pt
System
Pericard fld
Scale
Qn
Method

Additional Names

Long Common Name
Mononuclear cells/Leukocytes in Pericardial fluid
Short Name
Mononuc Cells NFr Pcar
Display Name
Mononuclear cells/Leukocytes (Pericard fld)
Consumer Name Alpha Get Info
Mononuclear cells/White Blood Cells, Pericardial fluid

Basic Attributes

Class
HEM/BC
Type
Laboratory
First Released
Version 2.22
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
59257-6 Cell count and Differential panel - Pericardial fluid
69741-7 Differential panel - Pericardial fluid

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Mononukleäre Zellen rel. /PPK
de-DE German (Germany) Mononukleäre Zellen/Leukozyten:Anzahl pro Fraktion:Zeitpunkt:Perikardflüssigkeit:Quantitativ:
el-GR Greek (Greece) Μονοπύρηνα κύτταρα/Λευκοκύτταρα:NFr:Pt:Περικαρδιακό υγρό:Qn:
Synonyms: NFr Κύτταρα Λευκοκύτταρα Μονοπύρηνα κύτταρα
es-ES Spanish (Spain) Mononucleares/Leucocitos:Fracción numérica:Punto temporal:Fluido pericárdico:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Células mononucleares / 100 leucocitos:Fracción numérica:Punto temporal:Líquido pericárdico:Cuantitativo:
fr-CA French (Canada) Cellules mononucléaires/Leucocytes:Fraction numérique:Temps ponctuel:Liquide péricardique:Quantitatif:
fr-FR French (France) Cellules mononucléées/100 leucocytes:Fraction de nombres:Ponctuel:Liquide péricardique:Numérique:
it-IT Italian (Italy) Cellule mononucleari/Leucociti:NFr:Pt:Liquido pericardico:Qn:
Synonyms: Ematologia (coagulazione) conta differenziale Frazione numerica Liquido pericardico Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) mononucleaire cellen/leukocyten:getalsfractie:moment:pericardvocht:kwantitatief:
pl-PL Polish (Poland) Mononuklearne komórki/leukocyty:frakcja liczbowa:punkt w czasie:płyn osierdziowy:ilościowy:
Synonyms: Leukocyty Mononuklearne komórki Mononuklearne komórki/leukocyty
pt-BR Portuguese (Brazil) Células mononucleares/100 leucócitos:NFr:Pt:LiqPeric:Qn:
Synonyms: ; Mononuc Cells; Leucoc; White blood cell; Leuc; Leuk; Leukocyte; Lkcs; White blood cells; Leucocs; Cell; Cellularity; 100Leucoc; Fr; Number fraction; Percent; Point in time; Random; Pcar; PCAR; Pericardial fluid; Quantitative; QNT; Quant; Quan; HEMATOLOGY/CELL COUNTS; HEMATOLOGY/CELL COUNTS
ru-RU Russian (Russian Federation) Мононуклеарные клетки/Лейкоциты:КолДоля:ТчкВрм:Перикардиальная ждк:Колич:
Synonyms: Количественный Количество отношение Перикардиальная жидкость Точка во времени;Момент
tr-TR Turkish (Turkey) Mononükleer hücreler/Lökosit:SayFr:Zmlı:Perikard sv:Kant:
zh-CN Chinese (China) 单个核细胞/白细胞:计数型分数:时间点:心包液:定量型:
Synonyms: Leuc;Leuk;Lkcs;WBC;WBCs;白细胞;White blood cell;WBC;白细胞类;白细胞类髓系细胞;白血球;白血细胞;白细胞数 单个核 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 心包积液;心包腔积液 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 细胞含量;细胞性;细胞性质;细胞构成;细胞类 血液学/细胞计数;血液学与细胞计数

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49782-6