Version 2.78

Part Descriptions

LP66701-1   Ganglioside
Ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (AKA n-acetylneuraminic acid, NANA) linked on the sugar chain. The 60+ known gangliosides differ mainly in the position and number of NANA residues.

It is a component of the cell plasma membrane that modulates cell signal transduction events. It appears that they concentrate in lipid rafts.

They have recently been found to be highly important in immunology. Natural and semisynthetic gangliosides are considered possible therapeutics for neurodegenerative disorders.

Gangliosides are more complex glycosphingolipids in which oligosaccharide chains containing N-acetylneuraminic acid (NeuNAc) are attached to a ceramide. NeuNAc, an acetylated derivative of the carbohydrate sialic acid, makes the head groups of Gangliosides anionic. NB: the M in GM2 stands for monosialo, i.e., one NeuNAc residue. GM2 is the second monosialo ganglioside characterized, thus the subscript 2. Their structural diversity results from variation in the composition and sequence of the sugar residues. In all Gangliosides, the ceramide is linked through its C-1 to a β-glucosyl residue, which, in turn, is bound to a β-galactosyl residue. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP222219-0   Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified. Source: Regenstrief LOINC

Fully-Specified Name

Component
Ganglioside Ab.IgG
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IB

Additional Names

Long Common Name
Ganglioside IgG Ab [Presence] in Serum by Immunoblot
Short Name
Ganglioside IgG Ser Ql IB
Display Name
Ganglioside IgG IB Ql (S)
Consumer Name Alpha Get Info
Ganglioside IgG antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.24
Last Updated
Version 2.58
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
82454-0 Ganglioside Ab panel - Serum by Immunoblot

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Ganglioside-AK IgG Immunoblot
es-ES Spanish (Spain) Gangliósido IgG:PrThr:Punto temporal:Suero:Ord:Inmunoblot (IB)
es-MX Spanish (Mexico) Gangliósido Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunotransferencia
et-EE Estonian (Estonia) Gangliosiid antikehad.IgG:PrThr:Pt:S:Ord:IB
Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Seerum
fr-CA French (Canada) Ganglioside, IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoblot
fr-FR French (France) Ganglioside anticorps IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoblot
fr-BE French (Belgium) Ganglioside Anticorps. IgG:PrThr:Temps ponctuel:Sérum:Ordinal:Immunoblot
Synonyms: Anticorps
it-IT Italian (Italy) Ganglioside Ab.IgG:PrThr:Pt:Siero:Ord:IB
Synonyms: anticorpi IgG anticorpo Immunoblot (IB) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) ganglioside As.IgG:aanwezigheid:moment:serum:ordinaal:immunoblotting
Synonyms: antistof; antilichaam IB
pt-BR Portuguese (Brazil) Gangliosideo Ac.IgG:ACnc:Pt:Soro:Ord:Imunoblot
Synonyms: Immune globulin G; Immunoglobulin G; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Western blot; WB; Immune blot; Immunobl; Blt; WBLOT; West blt; West blot; RIBA; Immunoblot; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU Russian (Russian Federation) Ганглиозид Ат.IgG:PrThr:ТчкВрм:Сыв:Пор:ИБ
Synonyms: Антитело Иммуноблот (ИБ) Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Gangliozid Ab.IgG:MevcEşik:Zmlı:Ser:Srl:IB
Synonyms: Ak Ak.IgG Mevcut
zh-CN Chinese (China) 神经节苷脂 抗体.IgG:存在情况或阈值:时间点:血清:序数型:免疫印迹法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫印迹;西部印迹法;Immunoblot;immunoblotting;IB 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 神经节糖苷 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=51701-1