Version 2.78

Part Description

LP32949-7   Lymphocyte proliferation
Ojo-Amaize, EA Lymphocyte Mitogen Stimulation. Lymphocyte mitogen stimulation assays are used for in vitro assessment of cellular immunity in patients with immunodeficiency, autoimmunity, infectious diseases, cancer and chemical-induced hypersensitivity reactions. Lymphocytes from healthy human subjects have receptors for mitogens such as the plant lectin concanavalin A (UCon A), pokeweed mitogen (PWM), the protein A component of Staphylococcus aureus Cowan strain I (SpA) and chemicals. Lymphocytes respond to these mitogens (substances that stimulate large numbers of lymphocytes without prior sensitization and in contrast to antigens do not require a sensitized host). Both B cells and T cells can be stimulated with mitogens. Inability of lymphocytes to respond to mitogens is a sign of impaired cell-mediated or humoral immunity.

There is a good correlation between CD4+ T-cell subset numbers and mitogenic response to PWM at different disease states in patients with HIV infection. [3H]-thymidine uptake is the gold standard for measuring lymphocyte mitogen stimulation.

However, a newer and more practical method utilizing supravital stains shows a good correlation with [3H]-thymidine uptake. Flow cytometry was also recently applied to analyze proliferation of cultured cells in response to stimulation with mitogen. Copyright Copyright © 1996 - 2008 Specialty Laboratories Source: Specialty Laboratories, Lymphocyte proliferation

Fully-Specified Name

Component
Lymphocyte proliferation
Property
Imp
Time
Pt
System
Bld
Scale
Nom
Method

Additional Names

Long Common Name
Lymphocyte proliferation [Interpretation] in Blood
Short Name
Lymphocyte prolif Bld-Imp
Display Name
Lymphocyte proliferation (Bld) [Interp]
Consumer Name Alpha Get Info
Lymphocyte proliferation, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.26
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
5477

Member of these Panels

LOINC Long Common Name
69042-0 Lymphocyte proliferation antigen panel - Blood by Flow cytometry (FC)
69018-0 Lymphocyte proliferation mitogen panel - Blood by Flow cytometry (FC)
59063-8 Lymphocyte proliferation panel - Blood

Member of these Groups Get Info

LOINC Group Group Name
LG21870-7 Lymphocyte proliferation|Imp|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Proliferación de linfocitos:Impresión/interpretación del estudio:Punto temporal:Sangre:Nom:
es-MX Spanish (Mexico) Proliferación de linfocitos:Impresión / interpretación del estudio:Punto temporal:Sangre:Nominal:
fr-CA French (Canada) Prolifération des lymphocytes:Impression:Temps ponctuel:Sang:Nominal:
fr-FR French (France) Lymphocytes prolifération:Interprétation:Ponctuel:Sang:Résultat nominal:
fr-BE French (Belgium) Prolifération des lymphocytes:Impression/interprétation d'étude:Temps ponctuel:Sang:Nominal:
it-IT Italian (Italy) Linfociti, proliferazione:Imp:Pt:Sangue:Nom:
Synonyms: Impressione/interpretazione di studio Proliferazione dei linfociti Punto nel tempo (episodio) Sangue Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) lymfocytenproliferatie:interpretatie:moment:bloed:nominaal:
pt-BR Portuguese (Brazil) Proliferação de linfócitos:Imp:Pt:SgTotal:Nom:
Synonyms: ; Lymphocyte prolif; Interpretation; Interp; Impression; Impressions; Point in time; Random; Blood; WB; Whole blood; Nominal; LPA; LPT; LST; Lymphocyte antigen proliferation; Lymphocyte antigen stimulation; PHA; Serology
ru-RU Russian (Russian Federation) Лимфоцит пролиферация:Впчт:ТчкВрм:Кр:Ном:
Synonyms: Впечатление/интерпретация исследования Кровь Номинальный;Именной Точка во времени;Момент
tr-TR Turkish (Turkey) Lenfosit proliferasyonu:İzlnm:Zmlı:Kan:Snf:
zh-CN Chinese (China) 淋巴细胞增殖:印象:时间点:全血:名义型:
Synonyms: LAP LAST LPA LPT LST PHA PHA 淋巴细胞转化试验 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 印象是一种诊断陈述，始终是对其他某种观察指标的解释或抽象（一系列检验项目结果、一幅图像或者整个某位病人），而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释 时刻;随机;随意;瞬间 植物血凝素 植物血凝素（phytohaemagglutinin，phytohemagglutinin，PHA） 淋巴细胞刺激试验 淋巴细胞刺激试验（Lymphocyte stimulation test，LST） 淋巴细胞增殖（Lymphocyte proliferation） 淋巴细胞增殖试验 淋巴细胞增殖试验（Lymphocyte proliferation test，LPT） 淋巴细胞抗原刺激试验 淋巴细胞抗原刺激试验（Lymphocyte antigen stimulation test，LAST） 淋巴细胞抗原增殖 淋巴细胞抗原增殖（Lymphocyte antigen proliferation，LAP） 淋巴细胞转化试验 淋巴细胞转化试验（lymphocyte proliferation assay，LPA，淋转） 淋转 血;血液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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CodeSystem lookup
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