57838-5
dRVVT W excess phospholipid (LA confirm)
Active
Term Description
If the coagulation defect corrects with excess phospholipid, it confirms the likely presence of phospholipid antibodies and the LA syndrome. Platelets, bilayer and hexagonal phospholipids are variously used as the source of excess phospholipids and this term covers them all. The use of one term for these variations reduces mapping work for practices that import laboratory results, but laboratories that use hexagonal phospholipids and think it important to distinguish their source can use 75883-9 instead of this term.
Source: Regenstrief LOINC
Part Descriptions
LP65493-6 Coagulation dilute Russell viper venom induced.excess phospholipid
Dilute Russell viper venom time (dRVVT) is a screening laboratory test for detecting the presence of lupus anticoagulants (LA), which are autoantibodies associated with excess clot formation, excess bleeding, and repeated miscarriages. The coagulant in the venom directly activates factor X, which turns prothrombin into thrombin in the presence of factor V and phospholipid. If phospholipid antibodies are present, this reaction will be inhibited, which will prolong the screening dRVVT and suggests the presence of LA. A confirmatory dRVVT test measures dRVVT in the presence of excess phospholipid, which saturates the antibody binding sites and thereby diminishes the inhibitory effect of the LA, resulting in a normalization of the dRVVT. The dRVVT screen to confirm ratio is calculated as Screen dRVVT/Confirm dRVVT, and the dRVVT percent correction is calculated as [(Screen dRVVT - Confirm dRVVT)/Screen dRVVT]x100. PMID: 19624461
Source: Regenstrief LOINC, PMID: 19624461
LP21280-0 Dilute Russell viper venom time
Dilute Russell's viper venom time (dRVVT) is a laboratory test for lupus anticoagulant (LA). This in vitro diagnostic test is based on the property that the venom of the Russell's Viper is effective at inducing thrombosis. The coagulant in the venom directly activates factor X, which turns prothrombin into thrombin in the presence of factor V and phospholipid. The venom is diluted to give a clotting time of 23 to 27 seconds and the phospholipid is reduced to make the test extremely sensitive to phospholipid. The dRVVT test is more sensitive than the aPTT test for the detection of lupus anticoagulant (an autoimmune disorder), because it is not influenced by deficiencies in clotting factors VIII, IX or XI. The dRVVT is thought to be more sensitive than the activated partial thromboplastin time (aPTT) for detection of lupus anticoagulants.
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Source: Wikipedia, Dilute Russell viper venom time (Wikipedia)
Fully-Specified Name
- Component
- Coagulation dilute Russell viper venom induced.excess phospholipid
- Property
- Time
- Time
- Pt
- System
- PPP
- Scale
- Qn
- Method
Additional Names
- Short Name
- Confirm dRVVT
- Display Name
- dRVVT excess phospholipid (PPP) [Time]
- Consumer Name Alpha Get Info
- dRVVT excess phospholipid, Blood
Basic Attributes
- Class
- COAG
- Type
- Laboratory
- First Released
- Version 2.29
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 1708
Member of these Panels
LOINC | Long Common Name |
---|---|
75515-7 | Lupus anticoagulant aPTT and dRVVT screening panel W Reflex |
75881-3 | Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: LA-Bestät. dRVVT |
de-DE | German (Germany) | Gerinnungszeit verdünntes Russell's Viper Venom-induziert (dRVVT).Phospholipidüberschuss: |
es-ES | Spanish (Spain) | Coagulación inducida por el veneno de vibora de Russell diluido. Exceso de fosfolípido: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Coagulación diluida por veneno de víbora de Russell inducida por exceso de fosfolípidos: |
fr-CA | French (Canada) | Coagulation induite par venin de vipère Russell dilué.en excès de phospholipides: |
fr-FR | French (France) | Temps de venin vipère Russell dilué en excès de phospholipides: |
fr-BE | French (Belgium) | Coagulation induite par venin de vip?re Russell dilué.en exc?s de phospholipides: Synonyms: DRVTT. Excès phopholipides DVRTT |
it-IT | Italian (Italy) | Coagulazione indotta da veleno diluito di vipera Russell.fosfolipidi in eccesso: Synonyms: Plasma povero di piastrine Punto nel tempo (episodio) Studio di coagulazione Tempo (e.g. secondi) Tempo di veleno diluito di vipera Russel (dRVVT) Tempo di veleno diluito di vipera Russel (dRVVT) f |
nl-NL | Dutch (Netherlands) | stolling, verdunde Russell viper venom-geïnduceerd.overmaat fosfolipide: Synonyms: coagulatiemethode stolling, verdunde Russell viper venom geinduceerd.overmaat fosfolipide |
pl-PL | Polish (Poland) | Krzepniecie indukowane rozcieńczonym jadem żmii Russella z nadmiarem fosfolipidów: Synonyms: PPP |
pt-BR | Portuguese (Brazil) | Coagulação diluida de Russel induzida por veneno de víbora.excesso de fosfolípides: Synonyms: Pl; |
ru-RU | Russian (Russian Federation) | Коагуляция Рассела виперы ядом индуцированная.избыток фосфолипидов: Synonyms: Время (в т.ч. в секундах) Количественный Обеднённая пластинками плазма; |
tr-TR | Turkish (Turkey) | Koagülasyon dilate Russell viper venom uyarılmış.fazla fosfolipid: |
zh-CN | Chinese (China) | 稀释蝰蛇毒诱导型凝血过程.过量磷脂: Synonyms: CRVV DDRVTVT dRVV dRVV 时间; |
Example Units
Unit | Source |
---|---|
s | Example UCUM Units |
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