Version 2.78

Term Description

Quantitative determination of ZnT8 Ab in serum or plasma. This term was created for, but not limited in use to, the BioVendor ZnT8 autoantibody (ZnT8 Ab) ELISA kit, which contains antibodies directed to the C terminal domain of ZnT8 (residues 268 - 369).
Source: Regenstrief LOINC

Part Descriptions

LP187079-1   Zinc transporter 8
A metallic element (Zn, atomic number 30 and atomic weight 65.38) necessary in the diet. It constitutes an essential part of many enzymes, and plays an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound healing and geophagia. Source: National Library of Medicine, MeSH 2006

LP187079-1   Zinc transporter 8
Zinc transporter 8 (ZnT8) is an islet beta-cell secretory membrane protein. ZnT8 autoantibodies (ZnT8A) are present in type 1 diabetes mellitus (DM) and are a marker for disease. When combined with established autoantibody markers, including glutamate decarboxylase (GADA), protein tyrosine phosphatase IA2 (IA2A), antibodies to insulin (IAA), and islet cytoplasmic autoantibodies (ICA), the ZnT8 antibody test improves diagnostic sensitivity in suspected cases of type 1 DM. PMID: 17942684 Source: Regenstrief LOINC, PMID:17942684

Fully-Specified Name

Component
Zinc transporter 8 Ab
Property
ACnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
IA

Additional Names

Short Name
ZnT8 Ab SerPl IA-aCnc
Display Name
Zinc transporter 8 Ab IA Qn
Consumer Name Alpha Get Info
Zinc transporter 8 antibody, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.52
Last Updated
Version 2.73
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
3752

Member of these Panels

LOINC Long Common Name
104673-9 Diabetes mellitus type 1 autoimmune panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Zink Transporter 8 AK
de-DE German (Germany) Zink-Transporter 8 Ak:Arbiträre Konzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:Immunoassay
es-ES Spanish (Spain) Transportador de Zinc 8 Anticuerpos:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Transportador de zinc 8 Ab:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:Inmunoensayo
fr-FR French (France) ZnT8 anticorps:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:Immunoanalyse
it-IT Italian (Italy) Zinc transporter 8 Ab:ACnc:Pt:Siero/Plasma:Qn:IA
Synonyms: anticorpo Chimica Concentrazione Arbitraria Immunoassay Plasma Punto nel tempo (episodio) Siero Siero o Plasma Trasportatore 8 dello zinco
nl-NL Dutch (Netherlands) zinc transporter 8 As:eenheid/volume:moment:serum of plasma:kwantitatief:immunoassay
Synonyms: antistof; antilichaam IA
tr-TR Turkish (Turkey) Çinko taşıyıcı 8 Ab:SçKons:Zmlı:Ser/Plaz:Kant:İA
Synonyms: Ak İmmünölçüm, immünoassay
zh-CN Chinese (China) 锌转运体 8 抗体:任意型浓度:时间点:血清/血浆:定量型:免疫测定法
Synonyms: Ab;自身抗体 Zn 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血清或血浆 锌转运蛋白 8;锌转运子 8;ZnT8;ZnT 8;ZnT-8

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=76651-9