79598-9

Beta alanine and Beta aminoisobutyrate and Gamma aminobutyrate pattern [Interpretation] in Urine Narrative

Active

Part Description

LP201667-5 Beta alanine & Beta aminoisobutyrate & Gamma aminobutyrate pattern
Changes in the CSF, plasma and urine levels of beta alanine, beta aminoisobutyrate (BAIB) and gamma aminobutyrate (GABA) may help identify certain metabolic disorders. Beta alanine is a structural analogue of GABA and may also function as a neurotransmitter since it is both a glycine and GABAA receptor agonist. Dihydropyrimidine dehydrogenase (DPD) is the first enzyme in the pyrimidine degradation pathway, in which uracil and thymine are catabolized to beta alanine and R-BAIB, respectively. The S enantiomer of BAIB (S-BAIB) is derived from valine catabolism. Under normal circumstances, urine contains predominantly R-BAIB (from thymine) because it is eliminated by filtration and tubular secretion, while plasma contains about 80% S-BAIB (from valine), which is reabsorbed in the kidneys. In patients with a DPD deficiency, uracil and thymine catabolism is decreased. This results in mildly decreased plasma and urine concentrations and normal CSF concentration of beta alanine, and moderately decreased CSF concentration and markedly decreased plasma concentration of BAIB. On the other hand, urine BAIB is elevated, which indicates that there must be cross-over in the thymine and valine degradation pathways. PMID: 14705962 Source: Regenstrief LOINC, PMID: 14705962

Fully-Specified Name

Component: Beta alanine & Beta aminoisobutyrate & Gamma aminobutyrate pattern
Property: Imp
Time: Pt
System: Urine
Scale: Nar
Method

Additional Names

Short Name: B-Alanine + B-AIB + GABA patt Ur-Imp
Display Name: Beta alanine and Beta aminoisobutyrate and Gamma aminobutyrate pattern Nar (U) [Interp]
Consumer Name Alpha Get Info: Interpretation of Beta alanine and beta aminoisobutyrate and Gamma aminobutyrate pattern test result, Urine

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.54
Last Updated: Version 2.56
Change Reason: Changed Class from CHEM.ESOTERIC to CHEM and added Esoteric tag for more flexibility
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
79584-9	Beta alanine and Beta aminoisobutyrate and Gamma aminobutyrate panel - Urine

Language Variants Get Info

Tag	Language	Translation
es-ES	Spanish (Spain)	Patrón de Beta alanina y Beta aminoisobutirato y Gamma aminobutirato:Impresión/interpretación del estudio:Punto temporal:Orina:Narrativo:
es-MX	Spanish (Mexico)	Patrón de beta alanina y beta aminoisobutirato y gamma aminobutirato:Impresión / interpretación del estudio:Punto temporal:Orina:Narrativo:
fr-FR	French (France)	Bêta alanine et bêta aminoisobutyrate et gamma aminoisobutyrate Profil:Interprétation:Ponctuel:Urine:Résultat textuel:
it-IT	Italian (Italy)	Beta alanina & Beta aminoisobutirrato & Gamma aminoisobutirrato, profilo:Imp:Pt:Urine:Nar: Synonyms: Chimica Impressione/interpretazione di studio Profilo di Beta alanina & Beta aminoisobutirrato & Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	bèta-alanine & bèta-aminoisobutyraat & gamma-aminobutyraat patroon:interpretatie:moment:urine:tekstueel: Synonyms: beta alanine & Beta aminoisobutyraat & Gamma aminobutyraat patroon
tr-TR	Turkish (Turkey)	Beta alanin ve Beta aminoizobütirat ve Gamma aminobutirat örüntüsü:İzlnm:Zmlı:İdrar:Öykü: Synonyms: Beta alanin ve Beta aminoizobütirat ve Gamma aminobutirat paterni
zh-CN	Chinese (China)	Beta 丙氨酸与 Beta 氨基异丁酸与 Gamma 氨基丁酸模式:印象:时间点:尿液:叙述型: Synonyms: 3-氨基异丁酸;B-AIB;Beta-氨基异丁酸;β氨基异丁酸;β-氨基异丁酸 4-氨基丁酸;GABA;Gamma 氨基丁酸（Gamma aminobutyric acid，GABA）;Gamma-氨基丁酸;G-氨基丁酸;γ氨基丁酸;γ-氨基丁酸;哌啶酸 Ala;Alpha 丙氨酸;Alpha-丙氨酸;L-Ala;L-丙氨酸;α丙氨酸;α-丙氨酸;丙胺酸 B B-Ala;Beta-丙氨酸;β丙氨酸;β-丙氨酸 Beta 丙氨酸（β丙氨酸、β-丙氨酸）与 Beta 氨基异丁酸（β氨基异丁酸、β-氨基异丁酸）与 Gamma 氨基丁酸（γ氨基丁酸、γ-氨基丁酸）模式（模式特征、特征模式、图谱、式样、组份、组分、成员） β 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类印象是一种诊断陈述，始终是对其他某种观察指标的解释或抽象（一系列检验项目结果、一幅图像或者整个某位病人），而且几乎总是由某位专业人员产生。;检查印象;检查印象/解释;检查的印象/解释;检查解释;解释;阐释叙述;叙述性文字;报告;报告型;文字叙述;文本叙述型;文本描述;文本描述型尿;小便;下泉时刻;随机;随意;瞬间氨基-n-丁酸氨基丁酸盐氨基丁酸酯贝塔

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