79774-6
a-wave amplitude Left retina dark-adapted by ERG
Active
Term Description
This term was developed in collaboration with the National Institute of Health's National Eye Institute (NEI) as part of an effort to standardize the data elements collected by the National Ophthalmic Disease Genotyping and Phenotyping Network (eyeGENE).
Source: Regenstrief LOINC
Part Descriptions
LP200585-0 a-wave amplitude
The a-wave is an electroretinographic measurement of the initial corneal-negative deflection, derived from the cones and rods of the outer photoreceptor layers. This wave reflects the hyperpolarization of the photoreceptors due to closure of sodium ion channels in the outer-segment membrane. Absorption of light triggers the rhodopsin to activate transducin, a G-protein, which leads to the activation of cyclic guanosine monophosphate phosphodiesterase (cGMP PDE) and eventually to a reduction in the level of cGMP within the photoreceptor. Reduction in cGMP leads to closure of the sodium ion channels, which results in a decrease of inwardly directed sodium ions, or hyperpolarization of the cell. The a-wave amplitude is measured from baseline to the trough of the a-wave.
Source: Regenstrief LOINC
LP200597-5 dark-adapted
Electrooculography (EOG) is a technique for measuring the resting potential of the retina. The EOG is used to assess the function of the pigment epithelium. During dark adaptation, the resting potential decreases slightly and reaches a minimum ("dark trough" or "Dt") after several minutes. When the light is switched on, a substantial increase of the resting potential occurs ("light peak" or "Lp"), which drops off after a few minutes when the retina adapts to the light. The ratio of the voltages (i.e., light peak divided by dark trough) is known as the Arden ratio and is normally above 1.80. The Arden ratio is often abnormal in retinitis pigmentosa, diabetic retinopathy, detached retina, Best disease and many other eye disorders.
Source: Regenstrief LOINC
LP203648-3 EYE.ERG.NEI
Developed in collaboration with the National Institute of Health's National Eye Institute (NEI) as part of an effort to standardize the data elements collected by the National Ophthalmic Disease Genotyping and Phenotyping Network (eyeGENE).
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- a-wave amplitude^dark-adapted
- Property
- Elpot
- Time
- Pt
- System
- Retina.left
- Scale
- Qn
- Method
- Electroretinogram
Additional Names
- Short Name
- a-wave amp L ret dark-adapt ERG
Basic Attributes
- Class
- EYE.ERG.NEI
- Type
- Clinical
- First Released
- Version 2.54
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
79894-2 | Electroretinography (ERG) panel |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-MX | Spanish (Mexico) | amplitud de onda a ^ adaptado a la oscuridad: |
it-IT | Italian (Italy) | onda A ampiezza^adattato al buio: Synonyms: Ampiezza dell''onda A Concetti di elettroretinografia NEI eyeGENE Elettroretinogramma Mediante ERG Occhio Potenziale Elettrico (Voltaggio) Punto nel tempo (episodio) Retina Sinistra |
zh-CN | Chinese (China) | a-波振幅^暗适应型: Synonyms: A 型 A 波幅度; |
Example Units
Unit | Source |
---|---|
mv | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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