Version 2.78

Part Description

LP64707-0   Bacterial carbapenem resistance blaKPC gene
Non-susceptibility to carbapenems in gram-negative bacilli by means of the enzyme KPC (Klebsiella pneumoniae carbapenemase) is becoming more common. The gene beta-lactamase KPC (bla(KPC)) encodes KPC enzyme production, which in turn hydrolyzes and inactivates carbapenem antibiotics. KPC enzymes are a class A beta lactamases with several variants (KPC-2, KPC-3, etc) known. Various methods are used to detect specific portions of genes encoding KPC production. Carbapenemases can also be detected by other methods, including the modified Hodge test to detect carbapenemase production in isolates and minimum inhibitory concentration (MIC) to determine level of resistance. Source: Regenstrief LOINC

Fully-Specified Name

Component
Bacterial carbapenem resistance blaKPC gene
Property
PrThr
Time
Pt
System
Isolate/Specimen
Scale
Ord
Method
Molgen

Additional Names

Short Name
blaKPC Islt/Spm Ql
Display Name
Carbapenem resistance blaKPC gene Molgen Ql (Islt/Spec)
Consumer Name Alpha Get Info
Carbapenem resistance blaKPC gene

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.22
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Corrected Component from "Bacterial carbapenemase resistance" to "Bacterial carbapenem resistance" (because the bacteria are resistant to carbapenem antibiotics by virtue of producing carbapenemase) and removed parentheses around and within the gene name according to recommended nomenclature [PMID: 25249841]; Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
Order vs. Observation
Both
Common Test Rank Get Info
1861

Member of these Panels

LOINC Long Common Name
104991-5 Bacterial resistance panel
85762-3 Blood pathogens panel by NAA with non-probe detection in Positive blood culture
97324-8 Carbapenem resistant bacteria identification and resistance panel by Molecular genetics method
85502-3 Carbapenemase resistance genes panel by Molecular genetics method
93698-9 Gram negative bacterial resistance panel by Molecular genetics method
93407-5 Gram negative blood culture panel by NAA with probe detection in Positive blood culture
97608-4 Joint pathogens panel - Synovial fluid by NAA with non-probe detection
92958-8 Respiratory pathogens DNA and RNA panel - Lower respiratory specimen by NAA with non-probe detection

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Carbapenem Resistenz Gen (blaKPC) ql.
de-DE German (Germany) Bakterielle Carbapenem-Resistenz blaKPC-Gen:Nachweis oder Schwellenwert:Zeitpunkt:Isolat oder Probenmaterial:Ordinal:Molekulargenetisch
es-ES Spanish (Spain) Gen bla(KPC):PrThr:Punto temporal:Muestra aislada:Ord:Genética molecular
es-MX Spanish (Mexico) Gen blaKPC de resistencia a carbapenémicos bacterianos:Presencia o umbral:Punto temporal:Aislado o espécimen:Ordinal:Genética molecular
fr-CA French (Canada) Gène bactérien de résistance à la carbapéném blaKPC:Présence-Seuil:Temps ponctuel:Isolat/Échantillon:Ordinal:Molgen
fr-FR French (France) Résistance bactérienne aux carbapénèmases blaKPC gène:Présence/Seuil:Ponctuel:Isolat/échantillon:Qualitatif:Biologie moléculaire
it-IT Italian (Italy) Resistenza batterica ai carbapenemici, gene blaKPC:PrThr:Pt:Isolato/Campione:Ord:Molgen
Synonyms: Gene blaKPC di resistenza batterica ai carbapenemici Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici
nl-NL Dutch (Netherlands) bacteriële carbapenemresistentie blaKPC-gen:aanwezigheid:moment:isolaat of monster:ordinaal:moleculair genetisch onderzoek
Synonyms: isolaat/specimen molgen
pt-BR Portuguese (Brazil) bla(KPC) gene:ACnc:Pt:Isolado:Ord:Sonda com limite de detecção da amplificação de alvo
Synonyms: Arbitrary concentration; Point in time; Random; Islt; Isol; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; ANTIBIOTIC SUSCEPTIBILITIES
zh-CN Chinese (China) 细菌碳青霉烯类耐药 blaKPC 基因:存在情况或阈值:时间点:分离株/标本:序数型:分子遗传学类实验室方法
Synonyms: 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 分离株/标本（样本、样品、试样） 分离物;分离菌;分离菌株;隔离种群 受检物 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 抗力 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 样品 样本 电阻 碳青霉烯类;碳青霉烯类抗生素 细菌性 细菌的 细菌碳青霉烯类（碳青霉烯类抗生素、碳青霉烯）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型） blaKPC 基因;细菌碳青霉烯酶（碳青黴烯酶、碳青霉烯水解酶）耐药（抗性、耐性、耐药性、抗药、抗药性、耐受、耐药型）blaKPC 基因 耐性 试样 遗传基因;遗传因子;吉恩;生物基因 阻力

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49617-4