85827-4
Carbapenem resistance bla OXA-48-like gene [Presence] by Molecular method
Active
Term Description
This test reports the presence of the OXA-48-like bacterial carbapenemase resistance type gene in gram negative bacterial isolates. This term was created for, but is not limited in use to, the submitter's modified protocol for the Check-Points Check-MDR CT103XL assay.
Source: Regenstrief LOINC
Part Description
LP248274-5 Bacterial carbapenem resistance blaOXA-48-like gene
The existence of OXA-48 like class D beta-lactamases has been increasing in enterobacter species organisms. The "OXA-like" groups of genes are molecularly similar to and thought to evolve from the original gene for which the group is named. For example, as of 2014 the blaOXA-23-like group included 19 genes, including including blaOXA-23, -27, -49, and -73. PMID: 24696435. The OXA-48 like class D beta-lactamase enzymes are highly resistant to penicillins and beta lactamase inhibitors and show a low resistance to carbapenems. These varied OXA-48-like beta-lactamases have been identified worldwide, including OXA-48-like producing Klebsiella pneumoniae with resistance to multiple drugs that emerged in Jordanian hospitals. Reports have shown that organisms producing OXA-48 like enzymes are either not resistant to broad-spectrum cephalosporins or show a decreased susceptibility to carbapenemase drugs. Identifying them can be a challenge. Screening and detection is required to prevent and control dissemination. PMID: 22499996 PMID: 26993738
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Bacterial carbapenem resistance blaOXA-48-like gene
- Property
- PrThr
- Time
- Pt
- System
- Isolate/Specimen
- Scale
- Ord
- Method
- Molgen
Additional Names
- Short Name
- blaOXA-48-like Islt/Spm Ql
- Display Name
- Carbapenem resistance bla OXA-48-like gene Molgen Ql (Islt/Spec)
- Consumer Name Alpha Get Info
- Carbapenem resistance bla OXA-48-like gene
Example Answer List: LL360-9
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.61
- Last Updated
- Version 2.67
- Change Reason
- Updated System from "Isolate" and Method from "Probe.amp.tar" according to the new, more sustainable model for LOINC molecular resistance terms [Approved by LOINC Laboratory Committee in June 2018].
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 104991-5 | Bacterial resistance panel |
| 97324-8 | Carbapenem resistant bacteria identification and resistance panel by Molecular genetics method |
| 85502-3 | Carbapenemase resistance genes panel by Molecular genetics method |
| 93698-9 | Gram negative bacterial resistance panel by Molecular genetics method |
| 97608-4 | Joint pathogens panel - Synovial fluid by NAA with non-probe detection |
| 92958-8 | Respiratory pathogens DNA and RNA panel - Lower respiratory specimen by NAA with non-probe detection |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Carbapenem Resistenz Gen (blaOXA-48-like) ql. |
| de-DE | German (Germany) | Bakterielle Carbapenem-Resistenz blaOXA-48-ähnliches Gen: |
| es-ES | Spanish (Spain) | gen bacteriano similar blaOXA-48 resistente a carbapenem: |
| es-MX | Spanish (Mexico) | Gen de tipo blaOXA-48 de resistencia a carbapenémicos bacterianos: |
| fr-FR | French (France) | Résistance bactérienne aux carbapénèmases blaOXA-48-like gène: |
| it-IT | Italian (Italy) | Resistenza batterica ai carbapenemici, gene blaOXA-48-like: Synonyms: Gene blaOXA-48-like di resistenza batterica ai carbapenemi Genetica molecolare Isolato o Campione Presenza o Soglia Punto nel tempo (episodio) Suscettibilità agli antibiotici |
| nl-NL | Dutch (Netherlands) | bacteriële carbapenemresistentie blaOXA-48-achtig gen: Synonyms: blaOXA-134-like isolaat/specimen molgen |
| zh-CN | Chinese (China) | 细菌碳青霉烯类耐药 blaOXA-48-样基因: Synonyms: 供检查用的材料; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=85827-4
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright